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PD-1 derived CA-170 is an oral immune checkpoint inhibitor that exhibits preclinical anti-tumor efficacy.
Commun Biol. 2021 Jun 8;4(1):699. doi: 10.1038/s42003-021-02191-1.
Commun Biol. 2021.
PMID: 34103659
Free PMC article.
Structure of cyclin-dependent kinase 2 (CDK2) in complex with the specific and potent inhibitor CVT-313.
Talapati SR, Nataraj V, Pothuganti M, Gore S, Ramachandra M, Antony T, More SS, Krishnamurthy NR.
Talapati SR, et al.
Acta Crystallogr F Struct Biol Commun. 2020 Aug 1;76(Pt 8):350-356. doi: 10.1107/S2053230X20009243. Epub 2020 Jul 28.
Acta Crystallogr F Struct Biol Commun. 2020.
PMID: 32744246
Free PMC article.
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Ternary complex formation of AFN-1252 with Acinetobacter baumannii FabI and NADH: Crystallographic and biochemical studies.
Rao NK, Nataraj V, Ravi M, Panchariya L, Palai K, Talapati SR, Lakshminarasimhan A, Ramachandra M, Antony T.
Rao NK, et al. Among authors: talapati sr.
Chem Biol Drug Des. 2020 Aug;96(2):704-713. doi: 10.1111/cbdd.13686. Epub 2020 Apr 22.
Chem Biol Drug Des. 2020.
PMID: 32227402
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Structural and binding studies of cyclin-dependent kinase 2 with NU6140 inhibitor.
Talapati SR, Goyal M, Nataraj V, Pothuganti M, R SM, Gore S, Ramachandra M, Antony T, More SS, Rao NK.
Talapati SR, et al.
Chem Biol Drug Des. 2021 Nov;98(5):857-868. doi: 10.1111/cbdd.13941. Epub 2021 Sep 5.
Chem Biol Drug Des. 2021.
PMID: 34423559
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