Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 2
1981 5
1982 6
1983 19
1984 27
1985 36
1986 32
1987 25
1988 27
1989 30
1990 24
1991 35
1992 26
1993 16
1994 15
1995 13
1996 14
1997 12
1998 12
1999 14
2000 12
2001 9
2002 5
2003 6
2004 4
2006 2
2007 3
2008 6
2009 2
2010 2
2011 1
2013 2
2014 3
2015 2
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

445 results

Results by year

Filters applied: . Clear all
Page 1
Talipexole protects dopaminergic neurons from methamphetamine toxicity in C57BL/6N mouse.
Kondo T, Shimada H, Hatori K, Sugita Y, Mizuno Y. Kondo T, et al. Neurosci Lett. 1998 May 15;247(2-3):143-6. doi: 10.1016/s0304-3940(98)00300-0. Neurosci Lett. 1998. PMID: 9655613
The effect of protection of dopaminergic neurons by talipexole, a dopamine (DA) agonist, is investigated on a methamphetamine (MA)-induced parkinsonism model of mice (C57BL/6N). ...In an in vitro experiment, talipexole inhibited the adduction reaction of hydroxyl ra …
The effect of protection of dopaminergic neurons by talipexole, a dopamine (DA) agonist, is investigated on a methamphetamine (MA)-in …
The neuroprotective effect of talipexole from paraquat-induced cell death in dopaminergic neuronal cells.
Gómez-Sánchez R, Bravo-San Pedro JM, Niso-Santano M, Soler G, Fuentes JM, González-Polo RA. Gómez-Sánchez R, et al. Neurotoxicology. 2010 Dec;31(6):701-8. doi: 10.1016/j.neuro.2010.07.005. Epub 2010 Jul 29. Neurotoxicology. 2010. PMID: 20673835
Talipexole is a non-ergot dopamine (DA) agonist that has been used in the treatment of Parkinson's disease. ...Pretreatment of N27 cells with talipexole (1mM) resulted in significant protection against paraquat-induced cell death. ...
Talipexole is a non-ergot dopamine (DA) agonist that has been used in the treatment of Parkinson's disease. ...Pretreatment of N27 ce …
Talipexole and adult Gilles de la Tourette's syndrome: double-blind, placebo-controlled clinical trial.
Goetz CG, Stebbins GT, Thelen JA. Goetz CG, et al. Mov Disord. 1994 May;9(3):315-7. doi: 10.1002/mds.870090306. Mov Disord. 1994. PMID: 7913738 Clinical Trial.
Talipexole is a new dopamine autoagonist with putative preferential activity on presynaptic dopamine receptors. ...Tics did not improve at tolerable doses. These findings suggest that talipexole has no role in the regular management of tic disorders....
Talipexole is a new dopamine autoagonist with putative preferential activity on presynaptic dopamine receptors. ...Tics did not impro …
Excitation by talipexole, a dopamine D2 agonist, of caudate nucleus neurons activated by nigral stimulation.
Todo N, Momiyama T, Amano T, Kohno Y, Sasa M. Todo N, et al. Life Sci. 1994;54(14):957-66. doi: 10.1016/0024-3205(94)00497-8. Life Sci. 1994. PMID: 7908115
This increase in firing by talipexole and quinpirole was blocked during simultaneous application of domperidone, although glutamate-induced firing remained unaffected by domperidone. In the CN neurons, in which the SN stimulation-induced spikes were not blocked by domperid …
This increase in firing by talipexole and quinpirole was blocked during simultaneous application of domperidone, although glutamate-i …
Protective effect of talipexole on MPTP-treated planarian, a unique parkinsonian worm model.
Kitamura Y, Kakimura J, Taniguchi T. Kitamura Y, et al. Jpn J Pharmacol. 1998 Sep;78(1):23-9. doi: 10.1254/jjp.78.23. Jpn J Pharmacol. 1998. PMID: 9804058 Free article.
Pramipexole showed a similar protective effect. In addition, post-treatment with talipexole at 1 hr after MPTP completely inhibited MPTP-induced individual death. ...These results suggest that the MPTP-treated planarian may be useful as a novel parkinsonian model in which …
Pramipexole showed a similar protective effect. In addition, post-treatment with talipexole at 1 hr after MPTP completely inhibited M …
Pharmacokinetic profile of talipexole in healthy volunteers is not altered when it is co-administered with Madopar (co-beneldopa).
Zhang TT, Song M, Hang TJ, Xu XF, Wen AD, Yang L, Jia L. Zhang TT, et al. J Clin Pharm Ther. 2009 Jun;34(3):345-54. doi: 10.1111/j.1365-2710.2008.01008.x. J Clin Pharm Ther. 2009. PMID: 19646081 Clinical Trial.
OBJECTIVES: To investigate the pharmacokinetics of talipexole hydrochloride tablets and the potential influence of Madopar (benserazide and levodopa combination; co-beneldopa) tablets on talipexole's pharmacokinetics when the two tablets are co-administered orally t …
OBJECTIVES: To investigate the pharmacokinetics of talipexole hydrochloride tablets and the potential influence of Madopar (benserazi …
Inhibition by talipexole, a thiazolo-azepine derivative, of dopaminergic neurons in the ventral tegmental area.
Momiyama T, Sasa M, Takaori S. Momiyama T, et al. Life Sci. 1991;49(7):535-43. doi: 10.1016/0024-3205(91)90071-i. Life Sci. 1991. PMID: 1677740
In type II neurons, however, the antidromic spikes were not affected by either talipexole or dopamine. Furthermore, spontaneous firing was also inhibited by iontophoretically applied talipexole and dopamine in most type I neurons, but rarely affected by either drug. …
In type II neurons, however, the antidromic spikes were not affected by either talipexole or dopamine. Furthermore, spontaneous firin …
Effects of talipexole on motor behavior in normal and MPTP-treated common marmosets.
Irifune M, Nomoto M, Fukuda T. Irifune M, et al. Eur J Pharmacol. 1993 Jul 20;238(2-3):235-40. doi: 10.1016/0014-2999(93)90852-9. Eur J Pharmacol. 1993. PMID: 8104807
These data for talipexole were very similar to those for bromocriptine. Talipexole had, however, several properties different from those of bromocriptine; it had a rapid onset of antiparkinsonian activity compared to bromocriptine; it had more than 25 times as much …
These data for talipexole were very similar to those for bromocriptine. Talipexole had, however, several properties different …
Antiparkinsonian activity of talipexole in MPTP-treated monkeys: in combination with L-dopa and as chronic treatment.
Irifune M, Nomoto M, Fukuda T. Irifune M, et al. Eur J Pharmacol. 1994 Oct 24;264(2):117-23. doi: 10.1016/0014-2999(94)00446-3. Eur J Pharmacol. 1994. PMID: 7851473
This may further support the postulated postsynaptic dopamine D2 receptor agonist properties of talipexole. Chronic treatment with talipexole (a daily dose of 40 micrograms/kg s.c. for 21 days) did not lead to tolerance to the antiparkinsonian activity in MPTP-treat …
This may further support the postulated postsynaptic dopamine D2 receptor agonist properties of talipexole. Chronic treatment with …
Talipexole or pramipexole combinations with chloro-APB (SKF 82958) in MPTP-induced hemiparkinsonian monkeys.
Domino EF, Ni L, Zhang H, Kohno Y, Sasa M. Domino EF, et al. Eur J Pharmacol. 1997 May 1;325(2-3):137-44. doi: 10.1016/s0014-2999(97)00129-5. Eur J Pharmacol. 1997. PMID: 9163560
Talipexole induced contraversive rotation in a dose-dependent manner up to 32 microg/kg, i.m. Talipexole was more potent than pramipexole (10 vs. 32 microg/kg, i.m.), but pramipexole was more efficacious in producing contraversive rotational behavior and significant …
Talipexole induced contraversive rotation in a dose-dependent manner up to 32 microg/kg, i.m. Talipexole was more potent than …
445 results