Tan A - Search Results

1

Chromatinized protein kinase C-θ directly regulates inducible genes in epithelial to mesenchymal transition and breast cancer stem cells.

Zafar A, Wu F, Hardy K, Li J, Tu WJ, McCuaig R, Harris J, Khanna KK, Attema J, Gregory PA, Goodall GJ, Harrington K, Dahlstrom JE, Boulding T, Madden R, Tan A, Milburn PJ, Rao S. Zafar A, et al. Among authors: tan a. Mol Cell Biol. 2014 Aug;34(16):2961-80. doi: 10.1128/MCB.01693-13. Epub 2014 Jun 2. Mol Cell Biol. 2014. PMID: 24891615 Free PMC article.

2

LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer.

Boulding T, McCuaig RD, Tan A, Hardy K, Wu F, Dunn J, Kalimutho M, Sutton CR, Forwood JK, Bert AG, Goodall GJ, Malik L, Yip D, Dahlstrom JE, Zafar A, Khanna KK, Rao S. Boulding T, et al. Among authors: tan a. Sci Rep. 2018 Jan 8;8(1):73. doi: 10.1038/s41598-017-17913-x. Sci Rep. 2018. PMID: 29311580 Free PMC article.

3

Nuclear-Biased DUSP6 Expression is Associated with Cancer Spreading Including Brain Metastasis in Triple-Negative Breast Cancer.

Wu F, McCuaig RD, Sutton CR, Tan AHY, Jeelall Y, Bean EG, Dai J, Prasanna T, Batham J, Malik L, Yip D, Dahlstrom JE, Rao S. Wu F, et al. Int J Mol Sci. 2019 Jun 24;20(12):3080. doi: 10.3390/ijms20123080. Int J Mol Sci. 2019. PMID: 31238530 Free PMC article.

4

Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch.

Tu WJ, McCuaig RD, Tan AHY, Hardy K, Seddiki N, Ali S, Dahlstrom JE, Bean EG, Dunn J, Forwood J, Tsimbalyuk S, Smith K, Yip D, Malik L, Prasanna T, Milburn P, Rao S. Tu WJ, et al. Front Immunol. 2020 Jun 16;11:1228. doi: 10.3389/fimmu.2020.01228. eCollection 2020. Front Immunol. 2020. PMID: 32612611 Free PMC article.

5

Selective Targeting of Protein Kinase C (PKC)-θ Nuclear Translocation Reduces Mesenchymal Gene Signatures and Reinvigorates Dysfunctional CD8⁺ T Cells in Immunotherapy-Resistant and Metastatic Cancers.

Dunn J, McCuaig RD, Tan AHY, Tu WJ, Wu F, Wagstaff KM, Zafar A, Ali S, Diwakar H, Dahlstrom JE, Bean EG, Forwood JK, Tsimbalyuk S, Cross EM, Hardy K, Bain AL, Ahern E, Dolcetti R, Mazzieri R, Yip D, Eastgate M, Malik L, Milburn P, Jans DA, Rao S. Dunn J, et al. Among authors: tan ahy. Cancers (Basel). 2022 Mar 21;14(6):1596. doi: 10.3390/cancers14061596. Cancers (Basel). 2022. PMID: 35326747 Free PMC article.

6

Author Correction: LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer.

Boulding T, McCuaig RD, Tan A, Hardy K, Wu F, Dunn J, Kalimutho M, Sutton CR, Forwood JK, Bert AG, Goodall GJ, Malik L, Yip D, Dahlstrom JE, Zafar A, Khanna KK, Rao S. Boulding T, et al. Among authors: tan a. Sci Rep. 2019 Dec 5;9(1):18771. doi: 10.1038/s41598-019-55020-1. Sci Rep. 2019. PMID: 31801957 Free PMC article.

7

Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4+ T cells through p65 and H2B phosphorylation.

Li J, Hardy K, Phetsouphanh C, Tu WJ, Sutcliffe EL, McCuaig R, Sutton CR, Zafar A, Munier CM, Zaunders JJ, Xu Y, Theodoratos A, Tan A, Lim PS, Knaute T, Masch A, Zerweck J, Brezar V, Milburn PJ, Dunn J, Casarotto MG, Turner SJ, Seddiki N, Kelleher AD, Rao S. Li J, et al. Among authors: tan a. J Cell Sci. 2016 Jun 15;129(12):2448-61. doi: 10.1242/jcs.181248. Epub 2016 May 5. J Cell Sci. 2016. PMID: 27149922 Free PMC article.

8

Priming of transcriptional memory responses via the chromatin accessibility landscape in T cells.

Tu WJ, Hardy K, Sutton CR, McCuaig R, Li J, Dunn J, Tan A, Brezar V, Morris M, Denyer G, Lee SK, Turner SJ, Seddiki N, Smith C, Khanna R, Rao S. Tu WJ, et al. Among authors: tan a. Sci Rep. 2017 Mar 20;7:44825. doi: 10.1038/srep44825. Sci Rep. 2017. PMID: 28317936 Free PMC article.

9

Lysine-Specific Histone Demethylase 1A Regulates Macrophage Polarization and Checkpoint Molecules in the Tumor Microenvironment of Triple-Negative Breast Cancer.

Tan AHY, Tu W, McCuaig R, Hardy K, Donovan T, Tsimbalyuk S, Forwood JK, Rao S. Tan AHY, et al. Front Immunol. 2019 Jun 12;10:1351. doi: 10.3389/fimmu.2019.01351. eCollection 2019. Front Immunol. 2019. PMID: 31249575 Free PMC article.

10

A Phase 1 Proof of Concept Study Evaluating the Addition of an LSD1 Inhibitor to Nab-Paclitaxel in Advanced or Metastatic Breast Cancer (EPI-PRIMED).

Prasanna T, Malik L, McCuaig RD, Tu WJ, Wu F, Lim PS, Tan AHY, Dahlstrom JE, Clingan P, Moylan E, Chrisp J, Fuller D, Rao S, Yip D. Prasanna T, et al. Front Oncol. 2022 Jun 3;12:862427. doi: 10.3389/fonc.2022.862427. eCollection 2022. Front Oncol. 2022. PMID: 35719960 Free PMC article.

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