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Resistance to targeted therapies as a multifactorial, gradual adaptation to inhibitor specific selective pressures.
Vander Velde R, Yoon N, Marusyk V, Durmaz A, Dhawan A, Miroshnychenko D, Lozano-Peral D, Desai B, Balynska O, Poleszhuk J, Kenian L, Teng M, Abazeed M, Mian O, Tan AC, Haura E, Scott J, Marusyk A. Vander Velde R, et al. Among authors: tan ac. Nat Commun. 2020 May 14;11(1):2393. doi: 10.1038/s41467-020-16212-w. Nat Commun. 2020. PMID: 32409712 Free PMC article.
Exogenous Thyroid Hormone Is Associated with Shortened Survival and Upregulation of High-Risk Gene Expression Profiles in Steroid Receptor-Positive Breast Cancers.
Wahdan-Alaswad RS, Edgerton SM, Salem H, Kim HM, Tan AC, Finlay-Schultz J, Wellberg EA, Sartorius CA, Jacobsen BM, Haugen BR, Liu B, Thor AD. Wahdan-Alaswad RS, et al. Among authors: tan ac. Clin Cancer Res. 2021 Jan 15;27(2):585-597. doi: 10.1158/1078-0432.CCR-20-2647. Epub 2020 Oct 23. Clin Cancer Res. 2021. PMID: 33097494
First-in-Class Inhibitors of Oncogenic CHD1L with Preclinical Activity against Colorectal Cancer.
Abbott JM, Zhou Q, Esquer H, Pike L, Broneske TP, Rinaldetti S, Abraham AD, Ramirez DA, Lunghofer PJ, Pitts TM, Regan DP, Tan AC, Gustafson DL, Messersmith WA, LaBarbera DV. Abbott JM, et al. Among authors: tan ac. Mol Cancer Ther. 2020 Aug;19(8):1598-1612. doi: 10.1158/1535-7163.MCT-20-0106. Epub 2020 Jun 4. Mol Cancer Ther. 2020. PMID: 32499299 Free PMC article.
482 results