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Engineering CAR-T cells to activate small-molecule drugs in situ.
Gardner TJ, Lee JP, Bourne CM, Wijewarnasuriya D, Kinarivala N, Kurtz KG, Corless BC, Dacek MM, Chang AY, Mo G, Nguyen KM, Brentjens RJ, Tan DS, Scheinberg DA. Gardner TJ, et al. Among authors: tan ds. Nat Chem Biol. 2022 Feb;18(2):216-225. doi: 10.1038/s41589-021-00932-1. Epub 2021 Dec 30. Nat Chem Biol. 2022. PMID: 34969970 Free PMC article.
Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia.
Minuesa G, Albanese SK, Xie W, Kazansky Y, Worroll D, Chow A, Schurer A, Park SM, Rotsides CZ, Taggart J, Rizzi A, Naden LN, Chou T, Gourkanti S, Cappel D, Passarelli MC, Fairchild L, Adura C, Glickman JF, Schulman J, Famulare C, Patel M, Eibl JK, Ross GM, Bhattacharya S, Tan DS, Leslie CS, Beuming T, Patel DJ, Goldgur Y, Chodera JD, Kharas MG. Minuesa G, et al. Among authors: tan ds. Nat Commun. 2019 Jun 19;10(1):2691. doi: 10.1038/s41467-019-10523-3. Nat Commun. 2019. PMID: 31217428 Free PMC article.
Functional Diversity of Gram-Negative Permeability Barriers Reflected in Antibacterial Activities and Intracellular Accumulation of Antibiotics.
Leus IV, Adamiak J, Chandar B, Bonifay V, Zhao S, Walker SS, Squadroni B, Balibar CJ, Kinarivala N, Standke LC, Voss HU, Tan DS, Rybenkov VV, Zgurskaya HI. Leus IV, et al. Among authors: tan ds. Antimicrob Agents Chemother. 2023 Feb 16;67(2):e0137722. doi: 10.1128/aac.01377-22. Epub 2023 Jan 30. Antimicrob Agents Chemother. 2023. PMID: 36715507 Free PMC article.
501 results