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The study of sequence configuration and functional impact of the (AC)n(AT)xTy motif in human beta-globin gene promoter.
Chan PK, Ma ES, Philipsen S, Tan-Un KC. Chan PK, et al. Am J Hematol. 2007 May;82(5):342-8. doi: 10.1002/ajh.20836. Am J Hematol. 2007. PMID: 17133428
Retinoic acid-induced human secretin gene expression in neuronal cells is mediated by cyclin-dependent kinase 1.
Lee LT, Tan-Un KC, Chow BK. Lee LT, et al. Ann N Y Acad Sci. 2006 Jul;1070:393-8. doi: 10.1196/annals.1317.051. Ann N Y Acad Sci. 2006. PMID: 16888198
Identification of a novel distal regulatory element of the human Neuroglobin gene by the chromosome conformation capture approach.
Tam KT, Chan PK, Zhang W, Law PP, Tian Z, Fung Chan GC, Philipsen S, Festenstein R, Tan-Un KC. Tam KT, et al. Among authors: tan un kc. Nucleic Acids Res. 2017 Jan 9;45(1):115-126. doi: 10.1093/nar/gkw820. Epub 2016 Sep 19. Nucleic Acids Res. 2017. PMID: 27651453 Free PMC article.
Localization and expression pattern of cytoglobin in carbon tetrachloride-induced liver fibrosis.
Man KN, Philipsen S, Tan-Un KC. Man KN, et al. Among authors: tan un kc. Toxicol Lett. 2008 Dec 15;183(1-3):36-44. doi: 10.1016/j.toxlet.2008.09.015. Epub 2008 Oct 1. Toxicol Lett. 2008. PMID: 18940239
The novel thiosemicarbazone, di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone (DpC), inhibits neuroblastoma growth in vitro and in vivo via multiple mechanisms.
Guo ZL, Richardson DR, Kalinowski DS, Kovacevic Z, Tan-Un KC, Chan GC. Guo ZL, et al. Among authors: tan un kc. J Hematol Oncol. 2016 Sep 27;9(1):98. doi: 10.1186/s13045-016-0330-x. J Hematol Oncol. 2016. PMID: 27678372 Free PMC article.
Functional and sequence analysis of human neuroglobin gene promoter region.
Zhang W, Tian Z, Sha S, Cheng LY, Philipsen S, Tan-Un KC. Zhang W, et al. Among authors: tan un kc. Biochim Biophys Acta. 2011 Apr-Jun;1809(4-6):236-44. doi: 10.1016/j.bbagrm.2011.02.003. Epub 2011 Mar 9. Biochim Biophys Acta. 2011. PMID: 21362510
5'HS5 of the human beta-globin locus control region is dispensable for the formation of the beta-globin active chromatin hub.
Chan PK, Wai A, Philipsen S, Tan-Un KC. Chan PK, et al. Among authors: tan un kc. PLoS One. 2008 May 7;3(5):e2134. doi: 10.1371/journal.pone.0002134. PLoS One. 2008. PMID: 18461170 Free PMC article.
Study of the hypoxia-dependent regulation of human CYGB gene.
Guo X, Philipsen S, Tan-Un KC. Guo X, et al. Biochem Biophys Res Commun. 2007 Dec 7;364(1):145-50. doi: 10.1016/j.bbrc.2007.09.108. Epub 2007 Oct 2. Biochem Biophys Res Commun. 2007. PMID: 17936249
Characterization of human cytoglobin gene promoter region.
Guo X, Philipsen S, Tan-Un KC. Guo X, et al. Biochim Biophys Acta. 2006 May;1759(5):208-15. doi: 10.1016/j.bbaexp.2006.04.002. Epub 2006 Apr 20. Biochim Biophys Acta. 2006. PMID: 16797742
Regulation of the human secretin gene is controlled by the combined effects of CpG methylation, Sp1/Sp3 ratio, and the E-box element.
Lee LT, Tan-Un KC, Pang RT, Lam DT, Chow BK. Lee LT, et al. Mol Endocrinol. 2004 Jul;18(7):1740-55. doi: 10.1210/me.2003-0461. Epub 2004 Apr 29. Mol Endocrinol. 2004. PMID: 15118068
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