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Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly.
Tanenbaum ME, Macůrek L, Galjart N, Medema RH. Tanenbaum ME, et al. EMBO J. 2008 Dec 17;27(24):3235-45. doi: 10.1038/emboj.2008.242. Epub 2008 Nov 20. EMBO J. 2008. PMID: 19020519 Free PMC article.
Balanced activity of three mitotic motors is required for bipolar spindle assembly and chromosome segregation.
van Heesbeen RG, Tanenbaum ME, Medema RH. van Heesbeen RG, et al. Among authors: tanenbaum me. Cell Rep. 2014 Aug 21;8(4):948-56. doi: 10.1016/j.celrep.2014.07.015. Epub 2014 Aug 7. Cell Rep. 2014. PMID: 25127142
Systematic dissection of dynein regulators in mitosis.
Raaijmakers JA, Tanenbaum ME, Medema RH. Raaijmakers JA, et al. Among authors: tanenbaum me. J Cell Biol. 2013 Apr 15;201(2):201-15. doi: 10.1083/jcb.201208098. J Cell Biol. 2013. PMID: 23589491 Free PMC article.
Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry.
Splinter D, Tanenbaum ME, Lindqvist A, Jaarsma D, Flotho A, Yu KL, Grigoriev I, Engelsma D, Haasdijk ED, Keijzer N, Demmers J, Fornerod M, Melchior F, Hoogenraad CC, Medema RH, Akhmanova A. Splinter D, et al. Among authors: tanenbaum me. PLoS Biol. 2010 Apr 6;8(4):e1000350. doi: 10.1371/journal.pbio.1000350. PLoS Biol. 2010. PMID: 20386726 Free PMC article.
Cyclin G-associated kinase promotes microtubule outgrowth from chromosomes during spindle assembly.
Tanenbaum ME, Vallenius T, Geers EF, Greene L, Mäkelä TP, Medema RH. Tanenbaum ME, et al. Chromosoma. 2010 Aug;119(4):415-24. doi: 10.1007/s00412-010-0267-8. Epub 2010 Mar 17. Chromosoma. 2010. PMID: 20237935 Free PMC article.
Kif15 cooperates with eg5 to promote bipolar spindle assembly.
Tanenbaum ME, Macůrek L, Janssen A, Geers EF, Alvarez-Fernández M, Medema RH. Tanenbaum ME, et al. Curr Biol. 2009 Nov 3;19(20):1703-11. doi: 10.1016/j.cub.2009.08.027. Epub 2009 Oct 8. Curr Biol. 2009. PMID: 19818618
RAMA1 is a novel kinetochore protein involved in kinetochore-microtubule attachment.
Raaijmakers JA, Tanenbaum ME, Maia AF, Medema RH. Raaijmakers JA, et al. Among authors: tanenbaum me. J Cell Sci. 2009 Jul 15;122(Pt 14):2436-45. doi: 10.1242/jcs.051912. Epub 2009 Jun 23. J Cell Sci. 2009. PMID: 19549680
The microtubule plus-end-tracking protein CLIP-170 associates with the spermatid manchette and is essential for spermatogenesis.
Akhmanova A, Mausset-Bonnefont AL, van Cappellen W, Keijzer N, Hoogenraad CC, Stepanova T, Drabek K, van der Wees J, Mommaas M, Onderwater J, van der Meulen H, Tanenbaum ME, Medema RH, Hoogerbrugge J, Vreeburg J, Uringa EJ, Grootegoed JA, Grosveld F, Galjart N. Akhmanova A, et al. Among authors: tanenbaum me. Genes Dev. 2005 Oct 15;19(20):2501-15. doi: 10.1101/gad.344505. Genes Dev. 2005. PMID: 16230537 Free PMC article.
CLIP-170 facilitates the formation of kinetochore-microtubule attachments.
Tanenbaum ME, Galjart N, van Vugt MA, Medema RH. Tanenbaum ME, et al. EMBO J. 2006 Jan 11;25(1):45-57. doi: 10.1038/sj.emboj.7600916. Epub 2005 Dec 15. EMBO J. 2006. PMID: 16362039 Free PMC article.
Nuclear envelope-associated dynein cooperates with Eg5 to drive prophase centrosome separation.
van Heesbeen RG, Raaijmakers JA, Tanenbaum ME, Medema RH. van Heesbeen RG, et al. Among authors: tanenbaum me. Commun Integr Biol. 2013 May 1;6(3):e23841. doi: 10.4161/cib.23841. Commun Integr Biol. 2013. PMID: 23713137 Free PMC article.
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