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ARHI: A new target of galactose toxicity in Classic Galactosemia.
Lai K, Tang M, Yin X, Klapper H, Wierenga K, Elsas L. Lai K, et al. Biosci Hypotheses. 2008;1(5):263-271. doi: 10.1016/j.bihy.2008.06.011. Biosci Hypotheses. 2008. PMID: 19122833 Free PMC article.
Innovative therapy for Classic Galactosemia - tale of two HTS.
Tang M, Odejinmi SI, Vankayalapati H, Wierenga KJ, Lai K. Tang M, et al. Mol Genet Metab. 2012 Jan;105(1):44-55. doi: 10.1016/j.ymgme.2011.09.028. Epub 2011 Oct 1. Mol Genet Metab. 2012. PMID: 22018723 Free PMC article. Review.
High-throughput screening for human galactokinase inhibitors.
Wierenga KJ, Lai K, Buchwald P, Tang M. Wierenga KJ, et al. J Biomol Screen. 2008 Jun;13(5):415-23. doi: 10.1177/1087057108318331. Epub 2008 May 19. J Biomol Screen. 2008. PMID: 18490662 Free PMC article.
Involvement of endoplasmic reticulum stress in a novel Classic Galactosemia model.
Slepak TI, Tang M, Slepak VZ, Lai K. Slepak TI, et al. Mol Genet Metab. 2007 Sep-Oct;92(1-2):78-87. doi: 10.1016/j.ymgme.2007.06.005. Epub 2007 Jul 20. Mol Genet Metab. 2007. PMID: 17643331 Free PMC article.
Assessment of ataxia phenotype in a new mouse model of galactose-1 phosphate uridylyltransferase (GALT) deficiency.
Chen W, Caston R, Balakrishnan B, Siddiqi A, Parmar K, Tang M, Feng M, Lai K. Chen W, et al. J Inherit Metab Dis. 2017 Jan;40(1):131-137. doi: 10.1007/s10545-016-9993-2. Epub 2016 Oct 25. J Inherit Metab Dis. 2017. PMID: 27783170 Free PMC article.
Galactose-1 phosphate uridylyltransferase (GalT) gene: A novel positive regulator of the PI3K/Akt signaling pathway in mouse fibroblasts.
Balakrishnan B, Chen W, Tang M, Huang X, Cakici DD, Siddiqi A, Berry G, Lai K. Balakrishnan B, et al. Biochem Biophys Res Commun. 2016 Jan 29;470(1):205-212. doi: 10.1016/j.bbrc.2016.01.036. Epub 2016 Jan 8. Biochem Biophys Res Commun. 2016. PMID: 26773505 Free PMC article.
Correlation assessment among clinical phenotypes, expression analysis and molecular modeling of 14 novel variations in the human galactose-1-phosphate uridylyltransferase gene.
Tang M, Facchiano A, Rachamadugu R, Calderon F, Mao R, Milanesi L, Marabotti A, Lai K. Tang M, et al. Hum Mutat. 2012 Jul;33(7):1107-15. doi: 10.1002/humu.22093. Epub 2012 Apr 30. Hum Mutat. 2012. PMID: 22461411 Free PMC article.
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