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Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation.
Huang J, Sabater-Lleal M, Asselbergs FW, Tregouet D, Shin SY, Ding J, Baumert J, Oudot-Mellakh T, Folkersen L, Johnson AD, Smith NL, Williams SM, Ikram MA, Kleber ME, Becker DM, Truong V, Mychaleckyj JC, Tang W, Yang Q, Sennblad B, Moore JH, Williams FM, Dehghan A, Silbernagel G, Schrijvers EM, Smith S, Karakas M, Tofler GH, Silveira A, Navis GJ, Lohman K, Chen MH, Peters A, Goel A, Hopewell JC, Chambers JC, Saleheen D, Lundmark P, Psaty BM, Strawbridge RJ, Boehm BO, Carter AM, Meisinger C, Peden JF, Bis JC, McKnight B, Öhrvik J, Taylor K, Franzosi MG, Seedorf U, Collins R, Franco-Cereceda A, Syvänen AC, Goodall AH, Yanek LR, Cushman M, Müller-Nurasyid M, Folsom AR, Basu S, Matijevic N, van Gilst WH, Kooner JS, Hofman A, Danesh J, Clarke R, Meigs JB; DIAGRAM Consortium; Kathiresan S, Reilly MP; CARDIoGRAM Consortium; Klopp N, Harris TB, Winkelmann BR, Grant PJ, Hillege HL, Watkins H; C4D Consortium; Spector TD, Becker LC, Tracy RP, März W, Uitterlinden AG, Eriksson P, Cambien F; CARDIOGENICS Consortium; Morange PE, Koenig W, Soranzo N, van der Harst P, Liu Y, O'Donnell CJ, Hamsten A. Huang J, et al. Among authors: tang w. Blood. 2012 Dec 6;120(24):4873-81. doi: 10.1182/blood-2012-06-436188. Epub 2012 Sep 18. Blood. 2012. PMID: 22990020 Free PMC article.
Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts.
Dehghan A, Yang Q, Peters A, Basu S, Bis JC, Rudnicka AR, Kavousi M, Chen MH, Baumert J, Lowe GD, McKnight B, Tang W, de Maat M, Larson MG, Eyhermendy S, McArdle WL, Lumley T, Pankow JS, Hofman A, Massaro JM, Rivadeneira F, Kolz M, Taylor KD, van Duijn CM, Kathiresan S, Illig T, Aulchenko YS, Volcik KA, Johnson AD, Uitterlinden AG, Tofler GH, Gieger C; Wellcome Trust Case Control Consortium; Psaty BM, Couper DJ, Boerwinkle E, Koenig W, O'Donnell CJ, Witteman JC, Strachan DP, Smith NL, Folsom AR. Dehghan A, et al. Among authors: tang w. Circ Cardiovasc Genet. 2009 Apr;2(2):125-33. doi: 10.1161/CIRCGENETICS.108.825224. Circ Cardiovasc Genet. 2009. PMID: 20031576 Free PMC article.
Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium.
Smith NL, Chen MH, Dehghan A, Strachan DP, Basu S, Soranzo N, Hayward C, Rudan I, Sabater-Lleal M, Bis JC, de Maat MP, Rumley A, Kong X, Yang Q, Williams FM, Vitart V, Campbell H, Mälarstig A, Wiggins KL, Van Duijn CM, McArdle WL, Pankow JS, Johnson AD, Silveira A, McKnight B, Uitterlinden AG; Wellcome Trust Case Control Consortium;; Aleksic N, Meigs JB, Peters A, Koenig W, Cushman M, Kathiresan S, Rotter JI, Bovill EG, Hofman A, Boerwinkle E, Tofler GH, Peden JF, Psaty BM, Leebeek F, Folsom AR, Larson MG, Spector TD, Wright AF, Wilson JF, Hamsten A, Lumley T, Witteman JC, Tang W, O'Donnell CJ. Smith NL, et al. Among authors: tang w. Circulation. 2010 Mar 30;121(12):1382-92. doi: 10.1161/CIRCULATIONAHA.109.869156. Epub 2010 Mar 15. Circulation. 2010. PMID: 20231535 Free PMC article.
Association of genomic loci from a cardiovascular gene SNP array with fibrinogen levels in European Americans and African-Americans from six cohort studies: the Candidate Gene Association Resource (CARe).
Wassel CL, Lange LA, Keating BJ, Taylor KC, Johnson AD, Palmer C, Ho LA, Smith NL, Lange EM, Li Y, Yang Q, Delaney JA, Tang W, Tofler G, Redline S, Taylor HA Jr, Wilson JG, Tracy RP, Jacobs DR Jr, Folsom AR, Green D, O'Donnell CJ, Reiner AP. Wassel CL, et al. Among authors: tang w. Blood. 2011 Jan 6;117(1):268-75. doi: 10.1182/blood-2010-06-289546. Epub 2010 Oct 26. Blood. 2011. PMID: 20978265 Free PMC article.
Genetic association analysis highlights new loci that modulate hematological trait variation in Caucasians and African Americans.
Lo KS, Wilson JG, Lange LA, Folsom AR, Galarneau G, Ganesh SK, Grant SF, Keating BJ, McCarroll SA, Mohler ER 3rd, O'Donnell CJ, Palmas W, Tang W, Tracy RP, Reiner AP, Lettre G. Lo KS, et al. Among authors: tang w. Hum Genet. 2011 Mar;129(3):307-17. doi: 10.1007/s00439-010-0925-1. Epub 2010 Dec 12. Hum Genet. 2011. PMID: 21153663 Free PMC article.
Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis.
Smith NL, Rice KM, Bovill EG, Cushman M, Bis JC, McKnight B, Lumley T, Glazer NL, van Hylckama Vlieg A, Tang W, Dehghan A, Strachan DP, O'Donnell CJ, Rotter JI, Heckbert SR, Psaty BM, Rosendaal FR. Smith NL, et al. Among authors: tang w. Blood. 2011 Jun 2;117(22):6007-11. doi: 10.1182/blood-2010-10-315473. Epub 2010 Dec 16. Blood. 2011. PMID: 21163921 Free PMC article. Clinical Trial.
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