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Short-chain fatty acids, GPR41 and GPR43 ligands, inhibit TNF-α-induced MCP-1 expression by modulating p38 and JNK signaling pathways in human renal cortical epithelial cells.
Kobayashi M, Mikami D, Kimura H, Kamiyama K, Morikawa Y, Yokoi S, Kasuno K, Takahashi N, Taniguchi T, Iwano M. Kobayashi M, et al. Among authors: taniguchi t. Biochem Biophys Res Commun. 2017 Apr 29;486(2):499-505. doi: 10.1016/j.bbrc.2017.03.071. Epub 2017 Mar 18. Biochem Biophys Res Commun. 2017. PMID: 28322790
Short-chain fatty acid mitigates adenine-induced chronic kidney disease via FFA2 and FFA3 pathways.
Mikami D, Kobayashi M, Uwada J, Yazawa T, Kamiyama K, Nishimori K, Nishikawa Y, Nishikawa S, Yokoi S, Kimura H, Kimura I, Taniguchi T, Iwano M. Mikami D, et al. Among authors: taniguchi t. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Jun;1865(6):158666. doi: 10.1016/j.bbalip.2020.158666. Epub 2020 Feb 13. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32061840
AR420626, a selective agonist of GPR41/FFA3, suppresses growth of hepatocellular carcinoma cells by inducing apoptosis via HDAC inhibition.
Mikami D, Kobayashi M, Uwada J, Yazawa T, Kamiyama K, Nishimori K, Nishikawa Y, Nishikawa S, Yokoi S, Taniguchi T, Iwano M. Mikami D, et al. Among authors: taniguchi t. Ther Adv Med Oncol. 2020 Mar 20;12:1758835920913432. doi: 10.1177/1758835920913432. eCollection 2020. Ther Adv Med Oncol. 2020. PMID: 33014144 Free PMC article.
Cyclooxygenase-2 is acutely induced by CCAAT/enhancer-binding protein β to produce prostaglandin E 2 and F 2α following gonadotropin stimulation in Leydig cells.
Yazawa T, Imamichi Y, Yuhki KI, Uwada J, Mikami D, Shimada M, Miyamoto K, Kitano T, Takahashi S, Sekiguchi T, Suzuki N, Rafiqul Islam Khan M, Ushikubi F, Umezawa A, Taniguchi T. Yazawa T, et al. Among authors: taniguchi t. Mol Reprod Dev. 2019 Jul;86(7):786-797. doi: 10.1002/mrd.23163. Epub 2019 May 13. Mol Reprod Dev. 2019. PMID: 31087493
4,318 results