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PPARγ activation attenuates opioid consumption and modulates mesolimbic dopamine transmission.
de Guglielmo G, Melis M, De Luca MA, Kallupi M, Li HW, Niswender K, Giordano A, Senzacqua M, Somaini L, Cippitelli A, Gaitanaris G, Demopulos G, Damadzic R, Tapocik J, Heilig M, Ciccocioppo R. de Guglielmo G, et al. Among authors: tapocik j. Neuropsychopharmacology. 2015 Mar;40(4):927-37. doi: 10.1038/npp.2014.268. Epub 2014 Sep 14. Neuropsychopharmacology. 2015. PMID: 25311134 Free PMC article.
PPARc activation attenuates opioid consumption and modulates mesolimbic dopamine transmission.
de Guglielmo G, Melis M, De Luca MA, Kallupi M, Li HW, Niswender K, Giordano A, Senzacqua M, Somaini L, Cippitelli A, Gaitanaris G, Demopulos G, Damadzic R, Tapocik J, Heilig M, Ciccocioppo R. de Guglielmo G, et al. Among authors: tapocik j. Neuropsychopharmacology. 2015 Mar;40(4):1052. doi: 10.1038/npp.2014.305. Neuropsychopharmacology. 2015. PMID: 25668637 Free PMC article. No abstract available.
A novel brain penetrant NPS receptor antagonist, NCGC00185684, blocks alcohol-induced ERK-phosphorylation in the central amygdala and decreases operant alcohol self-administration in rats.
Thorsell A, Tapocik JD, Liu K, Zook M, Bell L, Flanigan M, Patnaik S, Marugan J, Damadzic R, Dehdashti SJ, Schwandt ML, Southall N, Austin CP, Eskay R, Ciccocioppo R, Zheng W, Heilig M. Thorsell A, et al. Among authors: tapocik jd. J Neurosci. 2013 Jun 12;33(24):10132-42. doi: 10.1523/JNEUROSCI.4742-12.2013. J Neurosci. 2013. PMID: 23761908 Free PMC article.
Tacr1 gene variation and neurokinin 1 receptor expression is associated with antagonist efficacy in genetically selected alcohol-preferring rats.
Schank JR, Tapocik JD, Barbier E, Damadzic R, Eskay RL, Sun H, Rowe KE, King CE, Yao M, Flanigan ME, Solomon MG, Karlsson C, Cheng K, Rice KC, Heilig M. Schank JR, et al. Biol Psychiatry. 2013 Apr 15;73(8):774-81. doi: 10.1016/j.biopsych.2012.12.027. Epub 2013 Feb 16. Biol Psychiatry. 2013. PMID: 23419547 Free PMC article.
Wistar rats acquire and maintain self-administration of 20 % ethanol without water deprivation, saccharin/sucrose fading, or extended access training.
Augier E, Flanigan M, Dulman RS, Pincus A, Schank JR, Rice KC, Kejun C, Heilig M, Tapocik JD. Augier E, et al. Among authors: tapocik jd. Psychopharmacology (Berl). 2014 Dec;231(23):4561-8. doi: 10.1007/s00213-014-3605-3. Epub 2014 May 25. Psychopharmacology (Berl). 2014. PMID: 24858375 Free PMC article.
22 results