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Page 1
Discovery of a Potent and Selective Tyrosine Kinase 2 Inhibitor: TAK-279.
Leit S, Greenwood J, Carriero S, Mondal S, Abel R, Ashwell M, Blanchette H, Boyles NA, Cartwright M, Collis A, Feng S, Ghanakota P, Harriman GC, Hosagrahara V, Kaila N, Kapeller R, Rafi SB, Romero DL, Tarantino PM, Timaniya J, Toms AV, Wester RT, Westlin W, Srivastava B, Miao W, Tummino P, McElwee JJ, Edmondson SD, Masse CE. Leit S, et al. Among authors: tarantino pm. J Med Chem. 2023 Aug 10;66(15):10473-10496. doi: 10.1021/acs.jmedchem.3c00600. Epub 2023 Jul 10. J Med Chem. 2023. PMID: 37427891
Hybrid antibacterials. DNA polymerase-topoisomerase inhibitors.
Zhi C, Long ZY, Manikowski A, Comstock J, Xu WC, Brown NC, Tarantino PM Jr, Holm KA, Dix EJ, Wright GE, Barnes MH, Butler MM, Foster KA, LaMarr WA, Bachand B, Bethell R, Cadilhac C, Charron S, Lamothe S, Motorina I, Storer R. Zhi C, et al. Among authors: tarantino pm jr. J Med Chem. 2006 Feb 23;49(4):1455-65. doi: 10.1021/jm0510023. J Med Chem. 2006. PMID: 16480282 Free PMC article.