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A comparative study of 1-substituted imidazole and 1,2,4-triazole antifungal compounds as inhibitors of testosterone hydroxylations catalysed by mouse hepatic microsomal cytochromes P-450.
Ballard SA, Lodola A, Tarbit MH. Ballard SA, et al. Biochem Pharmacol. 1988 Dec 15;37(24):4643-51. doi: 10.1016/0006-2952(88)90333-4. Biochem Pharmacol. 1988. PMID: 3202901
Molecular modelling of CYP3A4 from an alignment with CYP102: identification of key interactions between putative active site residues and CYP3A-specific chemicals.
Lewis DF, Eddershaw PJ, Goldfarb PS, Tarbit MH. Lewis DF, et al. Xenobiotica. 1996 Oct;26(10):1067-86. doi: 10.3109/00498259609167423. Xenobiotica. 1996. PMID: 8905920
Molecular modelling of human CYP2C subfamily enzymes CYP2C9 and CYP2C19: rationalization of substrate specificity and site-directed mutagenesis experiments in the CYP2C subfamily.
Lewis DF, Dickins M, Weaver RJ, Eddershaw PJ, Goldfarb PS, Tarbit MH. Lewis DF, et al. Xenobiotica. 1998 Mar;28(3):235-68. doi: 10.1080/004982598239542. Xenobiotica. 1998. PMID: 9574814
Cytochrome P450 substrate specificities, substrate structural templates and enzyme active site geometries.
Lewis DF, Dickins M, Eddershaw PJ, Tarbit MH, Goldfarb PS. Lewis DF, et al. Among authors: tarbit mh. Drug Metabol Drug Interact. 1999;15(1):1-49. doi: 10.1515/dmdi.1999.15.1.1. Drug Metabol Drug Interact. 1999. PMID: 10707112 Review.
Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the putative active site of the human CYP2E1 isoform.
Lewis DF, Bird MG, Dickins M, Lake BG, Eddershaw PJ, Tarbit MH, Goldfarb PS. Lewis DF, et al. Among authors: tarbit mh. Xenobiotica. 2000 Jan;30(1):1-25. doi: 10.1080/004982500237794. Xenobiotica. 2000. PMID: 10659948
Molecular modelling of CYP1 family enzymes CYP1A1, CYP1A2, CYP1A6 and CYP1B1 based on sequence homology with CYP102.
Lewis DF, Lake BG, George SG, Dickins M, Eddershaw PJ, Tarbit MH, Beresford AP, Goldfarb PS, Guengerich FP. Lewis DF, et al. Among authors: tarbit mh. Toxicology. 1999 Nov 29;139(1-2):53-79. doi: 10.1016/s0300-483x(99)00098-0. Toxicology. 1999. PMID: 10614688
Molecular modelling of the human cytochrome P450 isoform CYP2A6 and investigations of CYP2A substrate selectivity.
Lewis DF, Dickins M, Lake BG, Eddershaw PJ, Tarbit MH, Goldfarb PS. Lewis DF, et al. Among authors: tarbit mh. Toxicology. 1999 Mar 1;133(1):1-33. doi: 10.1016/s0300-483x(98)00149-8. Toxicology. 1999. PMID: 10413191
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