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Toxoplasma exports dense granule proteins beyond the vacuole to the host cell nucleus and rewires the host genome expression.
Bougdour A, Tardieux I, Hakimi MA. Bougdour A, et al. Among authors: tardieux i. Cell Microbiol. 2014 Mar;16(3):334-43. doi: 10.1111/cmi.12255. Epub 2014 Jan 20. Cell Microbiol. 2014. PMID: 24373221 Review.
A role for Toxoplasma gondii type 1 ser/thr protein phosphatase in host cell invasion.
Delorme V, Garcia A, Cayla X, Tardieux I. Delorme V, et al. Among authors: tardieux i. Microbes Infect. 2002 Mar;4(3):271-8. doi: 10.1016/s1286-4579(02)01538-1. Microbes Infect. 2002. PMID: 11909736
SET8-mediated methylations of histone H4 lysine 20 mark silent heterochromatic domains in apicomplexan genomes.
Sautel CF, Cannella D, Bastien O, Kieffer S, Aldebert D, Garin J, Tardieux I, Belrhali H, Hakimi MA. Sautel CF, et al. Among authors: tardieux i. Mol Cell Biol. 2007 Aug;27(16):5711-24. doi: 10.1128/MCB.00482-07. Epub 2007 Jun 11. Mol Cell Biol. 2007. PMID: 17562855 Free PMC article.
Migration of Apicomplexa across biological barriers: the Toxoplasma and Plasmodium rides.
Tardieux I, Ménard R. Tardieux I, et al. Traffic. 2008 May;9(5):627-35. doi: 10.1111/j.1600-0854.2008.00703.x. Epub 2008 Jan 9. Traffic. 2008. PMID: 18194412 Free PMC article. Review.
Host cell entry by apicomplexa parasites requires actin polymerization in the host cell.
Gonzalez V, Combe A, David V, Malmquist NA, Delorme V, Leroy C, Blazquez S, Ménard R, Tardieux I. Gonzalez V, et al. Among authors: tardieux i. Cell Host Microbe. 2009 Mar 19;5(3):259-72. doi: 10.1016/j.chom.2009.01.011. Cell Host Microbe. 2009. PMID: 19286135
A Toxoplasma type 2C serine-threonine phosphatase is involved in parasite growth in the mammalian host cell.
Jan G, Delorme V, Saksouk N, Abrivard M, Gonzalez V, Cayla X, Hakimi MA, Tardieux I. Jan G, et al. Among authors: tardieux i. Microbes Infect. 2009 Oct;11(12):935-45. doi: 10.1016/j.micinf.2009.06.002. Epub 2009 Jun 27. Microbes Infect. 2009. PMID: 19563907
Independent roles of apical membrane antigen 1 and rhoptry neck proteins during host cell invasion by apicomplexa.
Giovannini D, Späth S, Lacroix C, Perazzi A, Bargieri D, Lagal V, Lebugle C, Combe A, Thiberge S, Baldacci P, Tardieux I, Ménard R. Giovannini D, et al. Among authors: tardieux i. Cell Host Microbe. 2011 Dec 15;10(6):591-602. doi: 10.1016/j.chom.2011.10.012. Cell Host Microbe. 2011. PMID: 22177563
Group B Streptococcus surface proteins as major determinants for meningeal tropism.
Tazi A, Bellais S, Tardieux I, Dramsi S, Trieu-Cuot P, Poyart C. Tazi A, et al. Among authors: tardieux i. Curr Opin Microbiol. 2012 Feb;15(1):44-9. doi: 10.1016/j.mib.2011.12.002. Epub 2011 Dec 27. Curr Opin Microbiol. 2012. PMID: 22206860 Review.
A Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation.
Braun L, Brenier-Pinchart MP, Yogavel M, Curt-Varesano A, Curt-Bertini RL, Hussain T, Kieffer-Jaquinod S, Coute Y, Pelloux H, Tardieux I, Sharma A, Belrhali H, Bougdour A, Hakimi MA. Braun L, et al. Among authors: tardieux i. J Exp Med. 2013 Sep 23;210(10):2071-86. doi: 10.1084/jem.20130103. Epub 2013 Sep 16. J Exp Med. 2013. PMID: 24043761 Free PMC article.
Apical membrane antigen 1 mediates apicomplexan parasite attachment but is dispensable for host cell invasion.
Bargieri DY, Andenmatten N, Lagal V, Thiberge S, Whitelaw JA, Tardieux I, Meissner M, Ménard R. Bargieri DY, et al. Among authors: tardieux i. Nat Commun. 2013;4:2552. doi: 10.1038/ncomms3552. Nat Commun. 2013. PMID: 24108241 Free PMC article.
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