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A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors.
Vigolo M, Chambers MG, Willen L, Chevalley D, Maskos K, Lammens A, Tardivel A, Das D, Kowalczyk-Quintas C, Schuepbach-Mallepell S, Smulski CR, Eslami M, Rolink A, Hummler E, Samy E, Fomekong Nanfack Y, Mackay F, Liao M, Hess H, Jiang X, Schneider P. Vigolo M, et al. Among authors: tardivel a. Nat Commun. 2018 Mar 23;9(1):1199. doi: 10.1038/s41467-018-03323-8. Nat Commun. 2018. PMID: 29572442 Free PMC article.
AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity.
Di Micco A, Frera G, Lugrin J, Jamilloux Y, Hsu ET, Tardivel A, De Gassart A, Zaffalon L, Bujisic B, Siegert S, Quadroni M, Broz P, Henry T, Hrycyna CA, Martinon F. Di Micco A, et al. Among authors: tardivel a. Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):E4671-80. doi: 10.1073/pnas.1602419113. Epub 2016 Jul 26. Proc Natl Acad Sci U S A. 2016. PMID: 27462105 Free PMC article.
The Nlrp3 inflammasome regulates acute graft-versus-host disease.
Jankovic D, Ganesan J, Bscheider M, Stickel N, Weber FC, Guarda G, Follo M, Pfeifer D, Tardivel A, Ludigs K, Bouazzaoui A, Kerl K, Fischer JC, Haas T, Schmitt-Gräff A, Manoharan A, Müller L, Finke J, Martin SF, Gorka O, Peschel C, Ruland J, Idzko M, Duyster J, Holler E, French LE, Poeck H, Contassot E, Zeiser R. Jankovic D, et al. Among authors: tardivel a. J Exp Med. 2013 Sep 23;210(10):1899-910. doi: 10.1084/jem.20130084. Epub 2013 Aug 26. J Exp Med. 2013. PMID: 23980097 Free PMC article.
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence.
Gross O, Poeck H, Bscheider M, Dostert C, Hannesschläger N, Endres S, Hartmann G, Tardivel A, Schweighoffer E, Tybulewicz V, Mocsai A, Tschopp J, Ruland J. Gross O, et al. Among authors: tardivel a. Nature. 2009 May 21;459(7245):433-6. doi: 10.1038/nature07965. Epub 2009 Apr 1. Nature. 2009. PMID: 19339971
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