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Flavonoids suppress human glioblastoma cell growth by inhibiting cell metabolism, migration, and by regulating extracellular matrix proteins and metalloproteinases expression.
Santos BL, Oliveira MN, Coelho PL, Pitanga BP, da Silva AB, Adelita T, Silva VD, Costa Mde F, El-Bachá RS, Tardy M, Chneiweiss H, Junier MP, Moura-Neto V, Costa SL. Santos BL, et al. Among authors: tardy m. Chem Biol Interact. 2015 Dec 5;242:123-38. doi: 10.1016/j.cbi.2015.07.014. Epub 2015 Sep 25. Chem Biol Interact. 2015. PMID: 26408079
Genotoxicity and morphological changes induced by the alkaloid monocrotaline, extracted from Crotalaria retusa, in a model of glial cells.
Silva-Neto JP, Barreto RA, Pitanga BP, Souza CS, Silva VD, Silva AR, Velozo ES, Cunha SD, Batatinha MJ, Tardy M, Ribeiro CS, Costa MF, El-Bachá RS, Costa SL. Silva-Neto JP, et al. Among authors: tardy m. Toxicon. 2010 Jan;55(1):105-17. doi: 10.1016/j.toxicon.2009.07.007. Epub 2009 Jul 15. Toxicon. 2010. PMID: 19615397
Antiproliferative, proapoptotic and morphogenic effects of the flavonoid rutin on human glioblastoma cells.
Santos BL, Silva AR, Pitanga BP, Sousa CS, Grangeiro MS, Fragomeni BO, Coelho PL, Oliveira MN, Menezes-Filho NJ, Costa MF, El-Bachá RS, Velozo ES, Sampaio GP, Freire SM, Tardy M, Costa SL. Santos BL, et al. Among authors: tardy m. Food Chem. 2011 Jul 15;127(2):404-11. doi: 10.1016/j.foodchem.2010.12.131. Epub 2011 Jan 8. Food Chem. 2011. PMID: 23140679
Flavonoids inhibit angiogenic cytokine production by human glioma cells.
Freitas S, Costa S, Azevedo C, Carvalho G, Freire S, Barbosa P, Velozo E, Schaer R, Tardy M, Meyer R, Nascimento I. Freitas S, et al. Among authors: tardy m. Phytother Res. 2011 Jun;25(6):916-21. doi: 10.1002/ptr.3338. Epub 2010 Dec 17. Phytother Res. 2011. PMID: 21170924
240 results