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Prefoldin prevents aggregation of α-synuclein.
Takano M, Tashiro E, Kitamura A, Maita H, Iguchi-Ariga SM, Kinjo M, Ariga H. Takano M, et al. Among authors: tashiro e. Brain Res. 2014 Jan 13;1542:186-94. Brain Res. 2014. PMID: 24511594
Prefoldin protects neuronal cells from polyglutamine toxicity by preventing aggregation formation.
Tashiro E, Zako T, Muto H, Itoo Y, Sörgjerd K, Terada N, Abe A, Miyazawa M, Kitamura A, Kitaura H, Kubota H, Maeda M, Momoi T, Iguchi-Ariga SM, Kinjo M, Ariga H. Tashiro E, et al. J Biol Chem. 2013 Jul 5;288(27):19958-72. doi: 10.1074/jbc.M113.477984. Epub 2013 May 17. J Biol Chem. 2013. PMID: 23720755 Free PMC article.
Prefoldin subunits are protected from ubiquitin-proteasome system-mediated degradation by forming complex with other constituent subunits.
Miyazawa M, Tashiro E, Kitaura H, Maita H, Suto H, Iguchi-Ariga SM, Ariga H. Miyazawa M, et al. Among authors: tashiro e. J Biol Chem. 2011 Jun 3;286(22):19191-203. doi: 10.1074/jbc.M110.216259. Epub 2011 Apr 8. J Biol Chem. 2011. PMID: 21478150 Free PMC article.
Rabring7 degrades c-Myc through complex formation with MM-1.
Narita R, Kitaura H, Torii A, Tashiro E, Miyazawa M, Ariga H, Iguchi-Ariga SM. Narita R, et al. Among authors: tashiro e. PLoS One. 2012;7(7):e41891. doi: 10.1371/journal.pone.0041891. Epub 2012 Jul 23. PLoS One. 2012. PMID: 22844532 Free PMC article.
We have reported that a novel c-Myc-binding protein, MM-1, repressed E-box-dependent transcription and transforming activities of c-Myc and that a mutation of A157R in MM-1, which is often observed in patients with leukemia or lymphoma, abrogated all of the repressive acti …
We have reported that a novel c-Myc-binding protein, MM-1, repressed E-box-dependent transcription and transforming activities of c-M …
Generation of incednine derivatives by mutasynthesis.
Miyanaga A, Takaku R, Takaishi M, Tashiro E, Kudo F, Eguchi T. Miyanaga A, et al. Among authors: tashiro e. J Antibiot (Tokyo). 2020 Jun 4. doi: 10.1038/s41429-020-0329-y. Online ahead of print. J Antibiot (Tokyo). 2020. PMID: 32499555
Ktedonoketone and 2'-oxosattabacin, benzenoid metabolites from a thermophilic bacterium Thermosporothrix hazakensis in the phylum Chloroflexi.
Igarashi Y, Yamamoto K, Ueno C, Yamada N, Saito K, Takahashi K, Enomoto M, Kuwahara S, Oikawa T, Tashiro E, Imoto M, Xiaohanyao Y, Zhou T, Harunari E, Oku N. Igarashi Y, et al. Among authors: tashiro e. J Antibiot (Tokyo). 2019 Sep;72(9):653-660. doi: 10.1038/s41429-019-0195-7. Epub 2019 Jun 5. J Antibiot (Tokyo). 2019. PMID: 31164714
14-3-3εa directs the pulsatile transport of basal factors toward the apical domain for lumen growth in tubulogenesis.
Mizotani Y, Suzuki M, Hotta K, Watanabe H, Shiba K, Inaba K, Tashiro E, Oka K, Imoto M. Mizotani Y, et al. Among authors: tashiro e. Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):E8873-E8881. doi: 10.1073/pnas.1808756115. Epub 2018 Aug 29. Proc Natl Acad Sci U S A. 2018. PMID: 30158171 Free PMC article.
Nonthmicin, a Polyether Polyketide Bearing a Halogen-Modified Tetronate with Neuroprotective and Antiinvasive Activity from Actinomadura sp.
Igarashi Y, Matsuoka N, In Y, Kataura T, Tashiro E, Saiki I, Sudoh Y, Duangmal K, Thamchaipenet A. Igarashi Y, et al. Among authors: tashiro e. Org Lett. 2017 Mar 17;19(6):1406-1409. doi: 10.1021/acs.orglett.7b00318. Epub 2017 Mar 3. Org Lett. 2017. PMID: 28256141
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