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Chemical chaperones interfere with the formation of scrapie prion protein.
Tatzelt J, Prusiner SB, Welch WJ. Tatzelt J, et al. EMBO J. 1996 Dec 2;15(23):6363-73. EMBO J. 1996. PMID: 8978663 Free PMC article.
Scrapie prions selectively modify the stress response in neuroblastoma cells.
Tatzelt J, Zuo J, Voellmy R, Scott M, Hartl U, Prusiner SB, Welch WJ. Tatzelt J, et al. Proc Natl Acad Sci U S A. 1995 Mar 28;92(7):2944-8. doi: 10.1073/pnas.92.7.2944. Proc Natl Acad Sci U S A. 1995. PMID: 7708753 Free PMC article.
Scrapie in mice deficient in apolipoprotein E or glial fibrillary acidic protein.
Tatzelt J, Maeda N, Pekny M, Yang SL, Betsholtz C, Eliasson C, Cayetano J, Camerino AP, DeArmond SJ, Prusiner SB. Tatzelt J, et al. Neurology. 1996 Aug;47(2):449-53. doi: 10.1212/wnl.47.2.449. Neurology. 1996. PMID: 8757019
A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis.
Schätzl HM, Laszlo L, Holtzman DM, Tatzelt J, DeArmond SJ, Weiner RI, Mobley WC, Prusiner SB. Schätzl HM, et al. J Virol. 1997 Nov;71(11):8821-31. doi: 10.1128/JVI.71.11.8821-8831.1997. J Virol. 1997. PMID: 9343242 Free PMC article.
Padula, J. L. Roberts, and R. I. Weiner, Neuron 5:1-10, 1990), was examined for its ability to support prion formation. We found that GT1 cells could be persistently infected with mouse RML prions and that conditioned medium from infected cells could transfer prions to uni …
Padula, J. L. Roberts, and R. I. Weiner, Neuron 5:1-10, 1990), was examined for its ability to support prion formation. We found that …
Propagation of prion strains through specific conformers of the prion protein.
Scott MR, Groth D, Tatzelt J, Torchia M, Tremblay P, DeArmond SJ, Prusiner SB. Scott MR, et al. J Virol. 1997 Dec;71(12):9032-44. doi: 10.1128/JVI.71.12.9032-9044.1997. J Virol. 1997. PMID: 9371560 Free PMC article.
Prion protein expression in Chinese hamster ovary cells using a glutamine synthetase selection and amplification system.
Blochberger TC, Cooper C, Peretz D, Tatzelt J, Griffith OH, Baldwin MA, Prusiner SB. Blochberger TC, et al. Protein Eng. 1997 Dec;10(12):1465-73. doi: 10.1093/protein/10.12.1465. Protein Eng. 1997. PMID: 9543009
Abnormalities in stress proteins in prion diseases.
Tatzelt J, Voellmy R, Welch WJ. Tatzelt J, et al. Cell Mol Neurobiol. 1998 Dec;18(6):721-9. doi: 10.1023/a:1020646321841. Cell Mol Neurobiol. 1998. PMID: 9876878 Review.
Kinetics of prion protein accumulation in the CNS of mice with experimental scrapie.
Tatzelt J, Groth DF, Torchia M, Prusiner SB, DeArmond SJ. Tatzelt J, et al. J Neuropathol Exp Neurol. 1999 Dec;58(12):1244-9. doi: 10.1097/00005072-199912000-00005. J Neuropathol Exp Neurol. 1999. PMID: 10604749
Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease.
Gilch S, Winklhofer KF, Groschup MH, Nunziante M, Lucassen R, Spielhaupter C, Muranyi W, Riesner D, Tatzelt J, Schätzl HM. Gilch S, et al. EMBO J. 2001 Aug 1;20(15):3957-66. doi: 10.1093/emboj/20.15.3957. EMBO J. 2001. PMID: 11483499 Free PMC article.
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