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208 results
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Intense neutral drifts yield robust and evolvable consensus proteins.
Bershtein S, Goldin K, Tawfik DS. Bershtein S, et al. Among authors: tawfik ds. J Mol Biol. 2008 Jun 20;379(5):1029-44. doi: 10.1016/j.jmb.2008.04.024. Epub 2008 Apr 16. J Mol Biol. 2008. PMID: 18495157
Perspectives in protein engineering and complementary technologies, Oxford, UK, September 13-17, 1994. To design or select: that is the question.
Tawfik D, Rapley R. Tawfik D, et al. Mol Biotechnol. 1995 Apr;3(2):172-3. doi: 10.1007/BF02789114. Mol Biotechnol. 1995. PMID: 7620978 No abstract available.
Differences in the biochemical properties of esterolytic antibodies correlate with structural diversity.
Zemel R, Schindler DG, Tawfik DS, Eshhar Z, Green BS. Zemel R, et al. Among authors: tawfik ds. Mol Immunol. 1994 Feb;31(2):127-37. doi: 10.1016/0161-5890(94)90085-x. Mol Immunol. 1994. PMID: 8309476
Expression and characterization of recombinant single-chain Fv and Fv fragments derived from a set of catalytic antibodies.
Kim SH, Schindler DG, Lindner AB, Tawfik DS, Eshhar Z. Kim SH, et al. Among authors: tawfik ds. Mol Immunol. 1997 Aug-Sep;34(12-13):891-906. doi: 10.1016/s0161-5890(97)00096-5. Mol Immunol. 1997. PMID: 9464525
Conformational changes affect binding and catalysis by ester-hydrolysing antibodies.
Lindner AB, Eshhar Z, Tawfik DS. Lindner AB, et al. Among authors: tawfik ds. J Mol Biol. 1999 Jan 8;285(1):421-30. doi: 10.1006/jmbi.1998.2309. J Mol Biol. 1999. PMID: 9878416
Esterolytic antibodies as mechanistic and structural models of hydrolases-a quantitative analysis.
Lindner AB, Kim SH, Schindler DG, Eshhar Z, Tawfik DS. Lindner AB, et al. Among authors: tawfik ds. J Mol Biol. 2002 Jul 12;320(3):559-72. doi: 10.1016/s0022-2836(02)00418-7. J Mol Biol. 2002. PMID: 12096909
Directed evolution of mammalian paraoxonases PON1 and PON3 for bacterial expression and catalytic specialization.
Aharoni A, Gaidukov L, Yagur S, Toker L, Silman I, Tawfik DS. Aharoni A, et al. Among authors: tawfik ds. Proc Natl Acad Sci U S A. 2004 Jan 13;101(2):482-7. doi: 10.1073/pnas.2536901100. Epub 2003 Dec 26. Proc Natl Acad Sci U S A. 2004. PMID: 14695884 Free PMC article.
Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes.
Harel M, Aharoni A, Gaidukov L, Brumshtein B, Khersonsky O, Meged R, Dvir H, Ravelli RB, McCarthy A, Toker L, Silman I, Sussman JL, Tawfik DS. Harel M, et al. Among authors: tawfik ds. Nat Struct Mol Biol. 2004 May;11(5):412-9. doi: 10.1038/nsmb767. Epub 2004 Apr 18. Nat Struct Mol Biol. 2004. PMID: 15098021
The 'evolvability' of promiscuous protein functions.
Aharoni A, Gaidukov L, Khersonsky O, McQ Gould S, Roodveldt C, Tawfik DS. Aharoni A, et al. Among authors: tawfik ds. Nat Genet. 2005 Jan;37(1):73-6. doi: 10.1038/ng1482. Epub 2004 Nov 28. Nat Genet. 2005. PMID: 15568024
Directed evolution of protein inhibitors of DNA-nucleases by in vitro compartmentalization (IVC) and nano-droplet delivery.
Bernath K, Magdassi S, Tawfik DS. Bernath K, et al. Among authors: tawfik ds. J Mol Biol. 2005 Feb 4;345(5):1015-26. doi: 10.1016/j.jmb.2004.11.017. Epub 2004 Dec 7. J Mol Biol. 2005. PMID: 15644201
208 results
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