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REST is a novel prognostic factor and therapeutic target for medulloblastoma.
Taylor P, Fangusaro J, Rajaram V, Goldman S, Helenowski IB, MacDonald T, Hasselblatt M, Riedemann L, Laureano A, Cooper L, Gopalakrishnan V. Taylor P, et al. Mol Cancer Ther. 2012 Aug;11(8):1713-1723. doi: 10.1158/1535-7163.MCT-11-0990. Epub 2012 Jul 30. Mol Cancer Ther. 2012. PMID: 22848092 Free PMC article.
Transcriptional repressor REST drives lineage stage-specific chromatin compaction at Ptch1 and increases AKT activation in a mouse model of medulloblastoma.
Dobson THW, Tao RH, Swaminathan J, Maegawa S, Shaik S, Bravo-Alegria J, Sharma A, Kennis B, Yang Y, Callegari K, Haltom AR, Taylor P, Kogiso M, Qi L, Khatua S, Goldman S, Lulla RR, Fangusaro J, MacDonald TJ, Li XN, Hawkins C, Rajaram V, Gopalakrishnan V. Dobson THW, et al. Among authors: taylor p. Sci Signal. 2019 Jan 22;12(565):eaan8680. doi: 10.1126/scisignal.aan8680. Sci Signal. 2019. PMID: 30670636 Free PMC article.
6,214 results