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Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors.
O'Connor CM, Leonard D, Wiredja D, Avelar RA, Wang Z, Schlatzer D, Bryson B, Tokala E, Taylor SE, Upadhyay A, Sangodkar J, Gingras AC, Westermarck J, Xu W, DiFeo A, Brautigan DL, Haider S, Jackson M, Narla G. O'Connor CM, et al. Among authors: taylor se. Oncogene. 2020 Jan;39(3):703-717. doi: 10.1038/s41388-019-1012-2. Epub 2019 Sep 20. Oncogene. 2020. PMID: 31541192 Free PMC article.
The Highly Recurrent PP2A Aα-Subunit Mutation P179R Alters Protein Structure and Impairs PP2A Enzyme Function to Promote Endometrial Tumorigenesis.
Taylor SE, O'Connor CM, Wang Z, Shen G, Song H, Leonard D, Sangodkar J, LaVasseur C, Avril S, Waggoner S, Zanotti K, Armstrong AJ, Nagel C, Resnick K, Singh S, Jackson MW, Xu W, Haider S, DiFeo A, Narla G. Taylor SE, et al. Cancer Res. 2019 Aug 15;79(16):4242-4257. doi: 10.1158/0008-5472.CAN-19-0218. Epub 2019 May 29. Cancer Res. 2019. PMID: 31142515 Free PMC article.
Targeting PP2A in cancer: Combination therapies.
Mazhar S, Taylor SE, Sangodkar J, Narla G. Mazhar S, et al. Among authors: taylor se. Biochim Biophys Acta Mol Cell Res. 2019 Jan;1866(1):51-63. doi: 10.1016/j.bbamcr.2018.08.020. Epub 2018 Sep 1. Biochim Biophys Acta Mol Cell Res. 2019. PMID: 30401535 Free PMC article. Review.
The role of obesity in treatment planning for early-stage cervical cancer.
Rives TA, Orellana TJ, Mumford BS, Sukumvanich P, Courtney-Brooks M, Berger J, Conger J, Vargo JA, Beriwal S, Lesnock J, Wang L, Orr BC, Taylor SE. Rives TA, et al. Among authors: taylor se. Gynecol Oncol. 2024 Feb;181:60-67. doi: 10.1016/j.ygyno.2023.12.006. Epub 2023 Dec 21. Gynecol Oncol. 2024. PMID: 38134755
High resolution mapping of the tumor microenvironment using integrated single-cell, spatial and in situ analysis.
Janesick A, Shelansky R, Gottscho AD, Wagner F, Williams SR, Rouault M, Beliakoff G, Morrison CA, Oliveira MF, Sicherman JT, Kohlway A, Abousoud J, Drennon TY, Mohabbat SH; 10x Development Teams; Taylor SEB. Janesick A, et al. Among authors: taylor seb. Nat Commun. 2023 Dec 19;14(1):8353. doi: 10.1038/s41467-023-43458-x. Nat Commun. 2023. PMID: 38114474 Free PMC article.
438 results