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Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization.
Akhter A, Caution K, Abu Khweek A, Tazi M, Abdulrahman BA, Abdelaziz DH, Voss OH, Doseff AI, Hassan H, Azad AK, Schlesinger LS, Wewers MD, Gavrilin MA, Amer AO. Akhter A, et al. Among authors: tazi m. Immunity. 2012 Jul 27;37(1):35-47. doi: 10.1016/j.immuni.2012.05.001. Epub 2012 May 31. Immunity. 2012. PMID: 22658523 Free PMC article.
Biofilm-derived Legionella pneumophila evades the innate immune response in macrophages.
Abu Khweek A, Fernández Dávila NS, Caution K, Akhter A, Abdulrahman BA, Tazi M, Hassan H, Novotny LA, Bakaletz LO, Amer AO. Abu Khweek A, et al. Among authors: tazi m. Front Cell Infect Microbiol. 2013 May 27;3:18. doi: 10.3389/fcimb.2013.00018. eCollection 2013. Front Cell Infect Microbiol. 2013. PMID: 23750338 Free PMC article.
Elevated Mirc1/Mir17-92 cluster expression negatively regulates autophagy and CFTR (cystic fibrosis transmembrane conductance regulator) function in CF macrophages.
Tazi MF, Dakhlallah DA, Caution K, Gerber MM, Chang SW, Khalil H, Kopp BT, Ahmed AE, Krause K, Davis I, Marsh C, Lovett-Racke AE, Schlesinger LS, Cormet-Boyaka E, Amer AO. Tazi MF, et al. Autophagy. 2016 Nov;12(11):2026-2037. doi: 10.1080/15548627.2016.1217370. Autophagy. 2016. PMID: 27541364 Free PMC article.
Aging is associated with hypermethylation of autophagy genes in macrophages.
Khalil H, Tazi M, Caution K, Ahmed A, Kanneganti A, Assani K, Kopp B, Marsh C, Dakhlallah D, Amer AO. Khalil H, et al. Among authors: tazi m. Epigenetics. 2016 May 3;11(5):381-8. doi: 10.1080/15592294.2016.1144007. Epub 2016 Feb 24. Epigenetics. 2016. PMID: 26909551 Free PMC article.
The expression of Mirc1/Mir17-92 cluster in sputum samples correlates with pulmonary exacerbations in cystic fibrosis patients.
Krause K, Kopp BT, Tazi MF, Caution K, Hamilton K, Badr A, Shrestha C, Tumin D, Hayes D Jr, Robledo-Avila F, Hall-Stoodley L, Klamer BG, Zhang X, Partida-Sanchez S, Parinandi NL, Kirkby SE, Dakhlallah D, McCoy KS, Cormet-Boyaka E, Amer AO. Krause K, et al. J Cyst Fibros. 2018 Jul;17(4):454-461. doi: 10.1016/j.jcf.2017.11.005. Epub 2017 Dec 11. J Cyst Fibros. 2018. PMID: 29241629 Free PMC article.
Depletion of the ubiquitin-binding adaptor molecule SQSTM1/p62 from macrophages harboring cftr ΔF508 mutation improves the delivery of Burkholderia cenocepacia to the autophagic machinery.
Abdulrahman BA, Khweek AA, Akhter A, Caution K, Tazi M, Hassan H, Zhang Y, Rowland PD, Malhotra S, Aeffner F, Davis IC, Valvano MA, Amer AO. Abdulrahman BA, et al. Among authors: tazi m. J Biol Chem. 2013 Jan 18;288(3):2049-58. doi: 10.1074/jbc.M112.411728. Epub 2012 Nov 12. J Biol Chem. 2013. PMID: 23148214 Free PMC article.
145 results