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Tbx20 Is an Essential Regulator of Embryonic Heart Growth in Zebrafish.
Just S, Raphel L, Berger IM, Bühler A, Keßler M, Rottbauer W. Just S, et al. PLoS One. 2016 Dec 1;11(12):e0167306. doi: 10.1371/journal.pone.0167306. eCollection 2016. PLoS One. 2016. PMID: 27907103 Free PMC article.
The molecular mechanisms that regulate cardiomyocyte proliferation during embryonic heart growth are not completely deciphered yet. ...Interestingly, ectopic overexpression of Tbx20 in wild-type zebrafish embryos resulted, similar to the …
The molecular mechanisms that regulate cardiomyocyte proliferation during embryonic heart growth are not complet …
Tbx20 drives cardiac progenitor formation and cardiomyocyte proliferation in zebrafish.
Lu F, Langenbacher A, Chen JN. Lu F, et al. Dev Biol. 2017 Jan 15;421(2):139-148. doi: 10.1016/j.ydbio.2016.12.009. Epub 2016 Dec 8. Dev Biol. 2017. PMID: 27940156 Free PMC article.
Tbx20 is a T-box transcription factor that plays essential roles in the development and maintenance of the heart. ...Here we report the identification of a zebrafish tbx20 mutation that results in an inactive, truncated protein lacking an
Tbx20 is a T-box transcription factor that plays essential roles in the development and maintenance of the heart
Tbx20 regulates a genetic program essential to adult mouse cardiomyocyte function.
Shen T, Aneas I, Sakabe N, Dirschinger RJ, Wang G, Smemo S, Westlund JM, Cheng H, Dalton N, Gu Y, Boogerd CJ, Cai CL, Peterson K, Chen J, Nobrega MA, Evans SM. Shen T, et al. J Clin Invest. 2011 Dec;121(12):4640-54. doi: 10.1172/JCI59472. Epub 2011 Nov 14. J Clin Invest. 2011. PMID: 22080862 Free PMC article.
Human mutations in or variants of TBX20 are associated with congenital heart disease, cardiomyopathy, and arrhythmias. ...Our data provide insight into the mechanisms by which mutations in TBX20 cause adult heart disease in humans....
Human mutations in or variants of TBX20 are associated with congenital heart disease, cardiomyopathy, and arrhythmias. ...Our …
Ndrg4 is required for normal myocyte proliferation during early cardiac development in zebrafish.
Qu X, Jia H, Garrity DM, Tompkins K, Batts L, Appel B, Zhong TP, Baldwin HS. Qu X, et al. Dev Biol. 2008 May 15;317(2):486-96. doi: 10.1016/j.ydbio.2008.02.044. Epub 2008 Mar 6. Dev Biol. 2008. PMID: 18407257 Free PMC article.
We show that, during zebrafish embryonic development, ndrg4 is expressed exclusively in the embryonic heart, the central nervous system (CNS) and the sensory system. ...Together, our studies reveal an essential role of ndrg4 in regulat
We show that, during zebrafish embryonic development, ndrg4 is expressed exclusively in the embryonic heart