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Lipopolysaccharide sensing an important factor in the innate immune response to Gram-negative bacterial infections: benefits and hazards of LPS hypersensitivity.

Freudenberg MA, Tchaptchet S, Keck S, Fejer G, Huber M, Schütze N, Beutler B, Galanos C. Freudenberg MA, et al. Among authors: tchaptchet s. Immunobiology. 2008;213(3-4):193-203. doi: 10.1016/j.imbio.2007.11.008. Epub 2007 Dec 27. Immunobiology. 2008. PMID: 18406367 Review.

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TLR9-dependent and independent pathways drive activation of the immune system by Propionibacterium acnes.

Tchaptchet S, Gumenscheimer M, Kalis C, Freudenberg N, Hölscher C, Kirschning CJ, Lamers M, Galanos C, Freudenberg MA. Tchaptchet S, et al. PLoS One. 2012;7(6):e39155. doi: 10.1371/journal.pone.0039155. Epub 2012 Jun 22. PLoS One. 2012. PMID: 22745710 Free PMC article.

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Absence of TRIF signaling in lipopolysaccharide-stimulated murine mast cells.

Keck S, Müller I, Fejer G, Savic I, Tchaptchet S, Nielsen PJ, Galanos C, Huber M, Freudenberg MA. Keck S, et al. Among authors: tchaptchet s. J Immunol. 2011 May 1;186(9):5478-88. doi: 10.4049/jimmunol.1000458. Epub 2011 Mar 25. J Immunol. 2011. PMID: 21441453 Free article.

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Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel.

Schmidt M, Raghavan B, Müller V, Vogl T, Fejer G, Tchaptchet S, Keck S, Kalis C, Nielsen PJ, Galanos C, Roth J, Skerra A, Martin SF, Freudenberg MA, Goebeler M. Schmidt M, et al. Among authors: tchaptchet s. Nat Immunol. 2010 Sep;11(9):814-9. doi: 10.1038/ni.1919. Epub 2010 Aug 15. Nat Immunol. 2010. PMID: 20711192

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Innate, antigen-independent role for T cells in the activation of the immune system by Propionibacterium acnes.

Tchaptchet S, Kirberg J, Freudenberg N, Schamel WW, Galanos C, Freudenberg MA. Tchaptchet S, et al. Eur J Immunol. 2010 Sep;40(9):2506-16. doi: 10.1002/eji.200939860. Eur J Immunol. 2010. PMID: 20690177 Free article.

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Requirement for TLR9 in the immunomodulatory activity of Propionibacterium acnes.

Kalis C, Gumenscheimer M, Freudenberg N, Tchaptchet S, Fejer G, Heit A, Akira S, Galanos C, Freudenberg MA. Kalis C, et al. Among authors: tchaptchet s. J Immunol. 2005 Apr 1;174(7):4295-300. doi: 10.4049/jimmunol.174.7.4295. J Immunol. 2005. PMID: 15778393 Free article.

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Immune response to Propionibacterium acnes in patients with sarcoidosis--in vivo and in vitro.

Schupp JC, Tchaptchet S, Lützen N, Engelhard P, Müller-Quernheim J, Freudenberg MA, Prasse A. Schupp JC, et al. Among authors: tchaptchet s. BMC Pulm Med. 2015 Jul 24;15:75. doi: 10.1186/s12890-015-0070-7. BMC Pulm Med. 2015. PMID: 26204953 Free PMC article.

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MyD88/TLR9 mediated immunopathology and gut microbiota dynamics in a novel murine model of intestinal graft-versus-host disease.

Heimesaat MM, Nogai A, Bereswill S, Plickert R, Fischer A, Loddenkemper C, Steinhoff U, Tchaptchet S, Thiel E, Freudenberg MA, Göbel UB, Uharek L. Heimesaat MM, et al. Among authors: tchaptchet s. Gut. 2010 Aug;59(8):1079-87. doi: 10.1136/gut.2009.197434. Gut. 2010. PMID: 20639251

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Surface-Associated Lipoproteins Link Enterococcus faecalis Virulence to Colitogenic Activity in IL-10-Deficient Mice Independent of Their Expression Levels.

Ocvirk S, Sava IG, Lengfelder I, Lagkouvardos I, Steck N, Roh JH, Tchaptchet S, Bao Y, Hansen JJ, Huebner J, Carroll IM, Murray BE, Sartor RB, Haller D. Ocvirk S, et al. Among authors: tchaptchet s. PLoS Pathog. 2015 Jun 12;11(6):e1004911. doi: 10.1371/journal.ppat.1004911. eCollection 2015 Jun. PLoS Pathog. 2015. PMID: 26067254 Free PMC article.

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Environmental Factors Modify the Severity of Acute DSS Colitis in Caspase-11-Deficient Mice.

Fan TJ, Tchaptchet SY, Arsene D, Mishima Y, Liu B, Sartor RB, Carroll IM, Miao EA, Fodor AA, Hansen JJ. Fan TJ, et al. Among authors: tchaptchet sy. Inflamm Bowel Dis. 2018 Oct 12;24(11):2394-2403. doi: 10.1093/ibd/izy244. Inflamm Bowel Dis. 2018. PMID: 30312415 Free PMC article.

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