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Probing the functional constraints of influenza A virus NEP by deep mutational scanning.
Teo QW, Wang Y, Lv H, Oade MS, Mao KJ, Tan TJC, Huan YW, Rivera-Cardona J, Shao EK, Choi D, Wang C, Tavakoli Dargani Z, Brooke CB, Te Velthuis AJW, Wu NC. Teo QW, et al. Among authors: te velthuis ajw. Cell Rep. 2025 Jan 28;44(1):115196. doi: 10.1016/j.celrep.2024.115196. Epub 2025 Jan 15. Cell Rep. 2025. PMID: 39817904 Free PMC article.
Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics.
Zhao N, Ho JSY, Meng F, Zheng S, Kurland AP, Tian L, Rea-Moreno M, Song X, Seo JS, Kaniskan HÜ, Te Velthuis AJW, Tortorella D, Chen YW, Johnson JR, Jin J, Marazzi I. Zhao N, et al. Among authors: te velthuis ajw. Cell Host Microbe. 2023 Jul 12;31(7):1154-1169.e10. doi: 10.1016/j.chom.2023.05.030. Epub 2023 Jun 5. Cell Host Microbe. 2023. PMID: 37339625 Free PMC article.
Spatio-temporal modelling of in vitro influenza A virus infection: the impact of defective interfering particles on type I interferon response.
Li Y, Nielsen BF, Levin SA, Te Velthuis AJW, Grenfell BT. Li Y, et al. Among authors: te velthuis ajw. bioRxiv [Preprint]. 2025 Nov 28:2025.10.09.681519. doi: 10.1101/2025.10.09.681519. bioRxiv. 2025. Update in: PLoS Comput Biol. 2026 Apr 22;22(4):e1014198. doi: 10.1371/journal.pcbi.1014198. PMID: 41278742 Free PMC article. Updated. Preprint.
RNA structure modulates Cas13 activity and enables mismatch detection.
Larsen BB, Kimchi O, Dunkley ORS, Grimm MS, Siegers JY, Huang Y, Vandavasi VG, Nguyen LT, Lamb CH, Aranovich I, Eggink D, Meijer A, Jalal H, Notterman DA, Karlsson EA, Te Velthuis AJW, Myhrvold C. Larsen BB, et al. Among authors: te velthuis ajw. Nat Biotechnol. 2025 Oct 23:10.1038/s41587-025-02868-6. doi: 10.1038/s41587-025-02868-6. Online ahead of print. Nat Biotechnol. 2025. PMID: 41131153 Free PMC article.
83 results