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Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling.
Tee AR, Fingar DC, Manning BD, Kwiatkowski DJ, Cantley LC, Blenis J. Tee AR, et al. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13571-6. doi: 10.1073/pnas.202476899. Epub 2002 Sep 23. Proc Natl Acad Sci U S A. 2002. PMID: 12271141 Free PMC article.
Localisation and regulation of the eIF4E-binding protein 4E-BP3.
Kleijn M, Scheper GC, Wilson ML, Tee AR, Proud CG. Kleijn M, et al. Among authors: tee ar. FEBS Lett. 2002 Dec 18;532(3):319-23. doi: 10.1016/s0014-5793(02)03694-3. FEBS Lett. 2002. PMID: 12482586
mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E.
Fingar DC, Richardson CJ, Tee AR, Cheatham L, Tsou C, Blenis J. Fingar DC, et al. Among authors: tee ar. Mol Cell Biol. 2004 Jan;24(1):200-16. doi: 10.1128/mcb.24.1.200-216.2004. Mol Cell Biol. 2004. PMID: 14673156 Free PMC article.
mTOR, translational control and human disease.
Tee AR, Blenis J. Tee AR, et al. Semin Cell Dev Biol. 2005 Feb;16(1):29-37. doi: 10.1016/j.semcdb.2004.11.005. Epub 2004 Dec 31. Semin Cell Dev Biol. 2005. PMID: 15659337 Review.
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