Tee AR - Search Results

1

The kinase triad, AMPK, mTORC1 and ULK1, maintains energy and nutrient homoeostasis.

Dunlop EA, Tee AR. Dunlop EA, et al. Among authors: tee ar. Biochem Soc Trans. 2013 Aug;41(4):939-43. doi: 10.1042/BST20130030. Biochem Soc Trans. 2013. PMID: 23863160 Review.

2

Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability.

Beugnet A, Tee AR, Taylor PM, Proud CG. Beugnet A, et al. Among authors: tee ar. Biochem J. 2003 Jun 1;372(Pt 2):555-66. doi: 10.1042/BJ20021266. Biochem J. 2003. PMID: 12611592 Free PMC article.

3

Analysis of mTOR signaling by the small G-proteins, Rheb and RhebL1.

Tee AR, Blenis J, Proud CG. Tee AR, et al. FEBS Lett. 2005 Aug 29;579(21):4763-8. doi: 10.1016/j.febslet.2005.07.054. FEBS Lett. 2005. PMID: 16098514

4

Hypoxia-inducible factor 1alpha is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif.

Land SC, Tee AR. Land SC, et al. Among authors: tee ar. J Biol Chem. 2007 Jul 13;282(28):20534-43. doi: 10.1074/jbc.M611782200. Epub 2007 May 14. J Biol Chem. 2007. PMID: 17502379

5

Mammalian target of rapamycin complex 1: signalling inputs, substrates and feedback mechanisms.

Dunlop EA, Tee AR. Dunlop EA, et al. Among authors: tee ar. Cell Signal. 2009 Jun;21(6):827-35. doi: 10.1016/j.cellsig.2009.01.012. Epub 2009 Jan 8. Cell Signal. 2009. PMID: 19166929 Review.

6

Mammalian target of rapamycin complex 1-mediated phosphorylation of eukaryotic initiation factor 4E-binding protein 1 requires multiple protein-protein interactions for substrate recognition.

Dunlop EA, Dodd KM, Seymour LA, Tee AR. Dunlop EA, et al. Among authors: tee ar. Cell Signal. 2009 Jul;21(7):1073-84. doi: 10.1016/j.cellsig.2009.02.024. Epub 2009 Mar 9. Cell Signal. 2009. PMID: 19272448

7

mTOR Ser-2481 autophosphorylation monitors mTORC-specific catalytic activity and clarifies rapamycin mechanism of action.

Soliman GA, Acosta-Jaquez HA, Dunlop EA, Ekim B, Maj NE, Tee AR, Fingar DC. Soliman GA, et al. Among authors: tee ar. J Biol Chem. 2010 Mar 12;285(11):7866-79. doi: 10.1074/jbc.M109.096222. Epub 2009 Dec 18. J Biol Chem. 2010. PMID: 20022946 Free PMC article.

8

Absence of the Birt-Hogg-Dubé gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility.

Preston RS, Philp A, Claessens T, Gijezen L, Dydensborg AB, Dunlop EA, Harper KT, Brinkhuizen T, Menko FH, Davies DM, Land SC, Pause A, Baar K, van Steensel MA, Tee AR. Preston RS, et al. Among authors: tee ar. Oncogene. 2011 Mar 10;30(10):1159-73. doi: 10.1038/onc.2010.497. Epub 2010 Nov 8. Oncogene. 2011. PMID: 21057536 Free PMC article.

9

Determining the pathogenicity of patient-derived TSC2 mutations by functional characterization and clinical evidence.

Dunlop EA, Dodd KM, Land SC, Davies PA, Martins N, Stuart H, McKee S, Kingswood C, Saggar A, Corderio I, Medeira AM, Kingston H, Sampson JR, Davies DM, Tee AR. Dunlop EA, et al. Among authors: tee ar. Eur J Hum Genet. 2011 Jul;19(7):789-95. doi: 10.1038/ejhg.2011.38. Epub 2011 Mar 16. Eur J Hum Genet. 2011. PMID: 21407264 Free PMC article.

10

ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding.

Dunlop EA, Hunt DK, Acosta-Jaquez HA, Fingar DC, Tee AR. Dunlop EA, et al. Among authors: tee ar. Autophagy. 2011 Jul;7(7):737-47. doi: 10.4161/auto.7.7.15491. Epub 2011 Jul 1. Autophagy. 2011. PMID: 21460630 Free PMC article.

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