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High-throughput protein production--lessons from scaling up from 10 to 288 recombinant proteins per week.
Tegel H, Steen J, Konrad A, Nikdin H, Pettersson K, Stenvall M, Tourle S, Wrethagen U, Xu L, Yderland L, Uhlén M, Hober S, Ottosson J. Tegel H, et al. Biotechnol J. 2009 Jan;4(1):51-7. doi: 10.1002/biot.200800183. Biotechnol J. 2009. PMID: 19039781
Parallel production and verification of protein products using a novel high-throughput screening method.
Tegel H, Yderland L, Boström T, Eriksson C, Ukkonen K, Vasala A, Neubauer P, Ottosson J, Hober S. Tegel H, et al. Biotechnol J. 2011 Aug;6(8):1018-25. doi: 10.1002/biot.201000430. Epub 2011 Jun 16. Biotechnol J. 2011. PMID: 21681961
Contribution of antibody-based protein profiling to the human Chromosome-centric Proteome Project (C-HPP).
Fagerberg L, Oksvold P, Skogs M, Algenäs C, Lundberg E, Pontén F, Sivertsson A, Odeberg J, Klevebring D, Kampf C, Asplund A, Sjöstedt E, Al-Khalili Szigyarto C, Edqvist PH, Olsson I, Rydberg U, Hudson P, Ottosson Takanen J, Berling H, Björling L, Tegel H, Rockberg J, Nilsson P, Navani S, Jirström K, Mulder J, Schwenk JM, Zwahlen M, Hober S, Forsberg M, von Feilitzen K, Uhlén M. Fagerberg L, et al. J Proteome Res. 2013 Jun 7;12(6):2439-48. doi: 10.1021/pr300924j. Epub 2012 Dec 31. J Proteome Res. 2013. PMID: 23276153
Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics.
Fagerberg L, Hallström BM, Oksvold P, Kampf C, Djureinovic D, Odeberg J, Habuka M, Tahmasebpoor S, Danielsson A, Edlund K, Asplund A, Sjöstedt E, Lundberg E, Szigyarto CA, Skogs M, Takanen JO, Berling H, Tegel H, Mulder J, Nilsson P, Schwenk JM, Lindskog C, Danielsson F, Mardinoglu A, Sivertsson A, von Feilitzen K, Forsberg M, Zwahlen M, Olsson I, Navani S, Huss M, Nielsen J, Ponten F, Uhlén M. Fagerberg L, et al. Mol Cell Proteomics. 2014 Feb;13(2):397-406. doi: 10.1074/mcp.M113.035600. Epub 2013 Dec 5. Mol Cell Proteomics. 2014. PMID: 24309898 Free PMC article.
Proteomics. Tissue-based map of the human proteome.
Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinoglu A, Sivertsson Å, Kampf C, Sjöstedt E, Asplund A, Olsson I, Edlund K, Lundberg E, Navani S, Szigyarto CA, Odeberg J, Djureinovic D, Takanen JO, Hober S, Alm T, Edqvist PH, Berling H, Tegel H, Mulder J, Rockberg J, Nilsson P, Schwenk JM, Hamsten M, von Feilitzen K, Forsberg M, Persson L, Johansson F, Zwahlen M, von Heijne G, Nielsen J, Pontén F. Uhlén M, et al. Science. 2015 Jan 23;347(6220):1260419. doi: 10.1126/science.1260419. Science. 2015. PMID: 25613900
Solid-phase cloning for high-throughput assembly of single and multiple DNA parts.
Lundqvist M, Edfors F, Sivertsson Å, Hallström BM, Hudson EP, Tegel H, Holmberg A, Uhlén M, Rockberg J. Lundqvist M, et al. Nucleic Acids Res. 2015 Apr 20;43(7):e49. doi: 10.1093/nar/gkv036. Epub 2015 Jan 23. Nucleic Acids Res. 2015. PMID: 25618848 Free PMC article.
Machine learning in computational biology to accelerate high-throughput protein expression.
Sastry A, Monk J, Tegel H, Uhlen M, Palsson BO, Rockberg J, Brunk E. Sastry A, et al. Bioinformatics. 2017 Aug 15;33(16):2487-2495. doi: 10.1093/bioinformatics/btx207. Bioinformatics. 2017. PMID: 28398465 Free PMC article.
Secretome-Based Screening in Target Discovery.
Ding M, Tegel H, Sivertsson Å, Hober S, Snijder A, Ormö M, Strömstedt PE, Davies R, Holmberg Schiavone L. Ding M, et al. Among authors: tegel h. SLAS Discov. 2020 Jul;25(6):535-551. doi: 10.1177/2472555220917113. Epub 2020 May 19. SLAS Discov. 2020. PMID: 32425085 Free PMC article.
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