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Renal transplantation, chronic dialysis, and chronic renal insufficiency in children and adolescents. The 1995 Annual Report of the North American Pediatric Renal Transplant Cooperative Study.
Warady BA, Hébert D, Sullivan EK, Alexander SR, Tejani A. Warady BA, et al. Among authors: tejani a. Pediatr Nephrol. 1997 Feb;11(1):49-64. doi: 10.1007/s004670050232. Pediatr Nephrol. 1997. PMID: 9035173
A randomized multicenter trial of OKT3 mAbs induction compared with intravenous cyclosporine in pediatric renal transplantation.
Benfield MR, Tejani A, Harmon WE, McDonald R, Stablein DM, McIntosh M, Rose S; CCTPT Study Group. Benfield MR, et al. Among authors: tejani a. Pediatr Transplant. 2005 Jun;9(3):282-92. doi: 10.1111/j.1399-3046.2005.00296.x. Pediatr Transplant. 2005. PMID: 15910382 Clinical Trial.
In patients treated with T cell antibody induction, retrospective data from the pediatric registry show a 22% reduction in the risk of graft failure. We conducted a randomized trial (n = 287) using OKT3 mAbs in one (OKT3) arm and intravenous cyclosporine in the othe …
In patients treated with T cell antibody induction, retrospective data from the pediatric registry show a 22% reduction in the risk o …
Predictive factors for delayed graft function (DGF) and its impact on renal graft survival in children: a report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS).
Tejani AH, Sullivan EK, Alexander SR, Fine RN, Harmon WE, Kohaut EC. Tejani AH, et al. Pediatr Transplant. 1999 Nov;3(4):293-300. doi: 10.1034/j.1399-3046.1999.00057.x. Pediatr Transplant. 1999. PMID: 10562974 Clinical Trial.

Censoring for primary non-function, GS for LD patients with a functioning graft at 30 d post-transplant and no DGF was 91.5%, compared to 70.1% for those with DGF (p < 0.001); GS for CD patients was 83.8% and 68.7%, respectively (p < 0.001). ...This large study revie

Censoring for primary non-function, GS for LD patients with a functioning graft at 30 d post-transplant and no DGF was 91.5%, compare …
Risk factors for posttransplant lymphoproliferative disorder (PTLD) in pediatric kidney transplantation: a report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS).
Dharnidharka VR, Sullivan EK, Stablein DM, Tejani AH, Harmon WE; North American Pediatric Renal Transplant Cooperative Study (NAPRTCS). Dharnidharka VR, et al. Among authors: tejani ah. Transplantation. 2001 Apr 27;71(8):1065-8. doi: 10.1097/00007890-200104270-00010. Transplantation. 2001. PMID: 11374404
In the same periods, the time to PTLD decreased from a median of 356 days (range 843048) to a median of 190 days (range 42-944). ...CONCLUSIONS: There is a trend towards increasing incidence and earlier occurrence of PTLD in the pediatric renal transplant pop …
In the same periods, the time to PTLD decreased from a median of 356 days (range 843048) to a median of 190 days (range 42-944 …
Pediatric renal transplantation--the NAPRTCS experience.
Tejani AH, Sullivan EK, Harmon WE, Fine RN, Kohaut E, Emmett L, Alexander SR. Tejani AH, et al. Clin Transpl. 1997:87-100. Clin Transpl. 1997. PMID: 9919393
Infants (below 2 years) have a higher mortality rate following transplantation compared to older children. Long-term (5-year) graft survival for children receiving a cadaver donor graft is 60%, and for living donor kidney recipients the graft survival is 76%. ...The …
Infants (below 2 years) have a higher mortality rate following transplantation compared to older children. Long-term (5-year) graft s …
The impact of donor source, recipient age, pre-operative immunotherapy and induction therapy on early and late acute rejections in children: a report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS).
Tejani AH, Stablein DM, Sullivan EK, Alexander SR, Fine RN, Harmon WE, Kohaut EC. Tejani AH, et al. Pediatr Transplant. 1998 Nov;2(4):318-24. Pediatr Transplant. 1998. PMID: 10084737
Acute rejection is a frequent event in pediatric transplantation. In addition to graft loss, acute rejection episodes stimulate the development of chronic rejection and inhibit growth in children post-transplantation. ...The high frequency of rejection episodes in children …
Acute rejection is a frequent event in pediatric transplantation. In addition to graft loss, acute rejection episodes stimulate the d …
Recombinant human growth hormone post-renal transplantation in children: a randomized controlled study of the NAPRTCS.
Fine RN, Stablein D, Cohen AH, Tejani A, Kohaut E. Fine RN, et al. Among authors: tejani a. Kidney Int. 2002 Aug;62(2):688-96. doi: 10.1046/j.1523-1755.2002.00489.x. Kidney Int. 2002. PMID: 12110034 Clinical Trial.
Therefore, a randomized controlled study was undertaken. METHODS: Sixty-eight growth retarded pediatric renal allograft recipients were enrolled in a one-year randomized controlled study to determine the efficacy and safety of rhGH. ...Prior to enrollment, more than …
Therefore, a randomized controlled study was undertaken. METHODS: Sixty-eight growth retarded pediatric renal allograft recipients we …
Safety and pharmacokinetics of ascending single doses of sirolimus (Rapamune, rapamycin) in pediatric patients with stable chronic renal failure undergoing dialysis.
Tejani A, Alexander S, Ettenger R, Lerner G, Zimmerman J, Kohaut E, Briscoe DM. Tejani A, et al. Pediatr Transplant. 2004 Apr;8(2):151-60. doi: 10.1046/j.1399-3046.2003.00137.x. Pediatr Transplant. 2004. PMID: 15049795 Clinical Trial.
This study reports on a phase 1 assessment of the drug's tolerance, safety, and pharmacokinetic parameters in pediatric patients. ...Sirolimus is well tolerated as a single dose of 1, 3, 9, or 15 mg/m(2)....
This study reports on a phase 1 assessment of the drug's tolerance, safety, and pharmacokinetic parameters in pediatric patients. ... …
Chronic renal insufficiency in children: the 2001 Annual Report of the NAPRTCS.
Seikaly MG, Ho PL, Emmett L, Fine RN, Tejani A. Seikaly MG, et al. Among authors: tejani a. Pediatr Nephrol. 2003 Aug;18(8):796-804. doi: 10.1007/s00467-003-1158-5. Epub 2003 Jun 14. Pediatr Nephrol. 2003. PMID: 12811650
End-stage renal disease (ESRD) is a major cause of morbidity in children. Besides its high cost to society, ESRD carries significant mortality. ...There was a correlation between CRI and several co-morbid clinical factors: low hematocrit, hypoalbuminemia, hypocalcem …
End-stage renal disease (ESRD) is a major cause of morbidity in children. Besides its high cost to society, ESRD carries significant …
Reduction in acute rejections decreases chronic rejection graft failure in children: a report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS).
Tejani A, Ho PL, Emmett L, Stablein DM; North American Pediatric Renal Transplant Cooperative Study (NAPRTCS). Tejani A, et al. Am J Transplant. 2002 Feb;2(2):142-7. doi: 10.1034/j.1600-6143.2002.020205.x. Am J Transplant. 2002. PMID: 12099516

In a previous study acute, multiple acute and late acute rejections were risk factors for the development of chronic rejection. ...A late initial rejection increased the risk of chronic rejection graft failure 3.6-fold (p < 0.001), while a second rejection

In a previous study acute, multiple acute and late acute rejections were risk factors for the development of chronic rejection. ... …
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