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Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2)-dependent oligomerization of fibroblast growth factor 2 (FGF2) triggers the formation of a lipidic membrane pore implicated in unconventional secretion.
Steringer JP, Bleicken S, Andreas H, Zacherl S, Laussmann M, Temmerman K, Contreras FX, Bharat TA, Lechner J, Müller HM, Briggs JA, García-Sáez AJ, Nickel W. Steringer JP, et al. Among authors: temmerman k. J Biol Chem. 2012 Aug 10;287(33):27659-69. doi: 10.1074/jbc.M112.381939. Epub 2012 Jun 23. J Biol Chem. 2012. PMID: 22730382 Free PMC article.
Phenotypic profiling of the human genome reveals gene products involved in plasma membrane targeting of SRC kinases.
Ritzerfeld J, Remmele S, Wang T, Temmerman K, Brügger B, Wegehingel S, Tournaviti S, Strating JR, Wieland FT, Neumann B, Ellenberg J, Lawerenz C, Hesser J, Erfle H, Pepperkok R, Nickel W. Ritzerfeld J, et al. Among authors: temmerman k. Genome Res. 2011 Nov;21(11):1955-68. doi: 10.1101/gr.116087.110. Epub 2011 Jul 27. Genome Res. 2011. PMID: 21795383 Free PMC article.
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