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An estrogen receptor-alpha knock-in mutation provides evidence of ligand-independent signaling and allows modulation of ligand-induced pathways in vivo.
Sinkevicius KW, Burdette JE, Woloszyn K, Hewitt SC, Hamilton K, Sugg SL, Temple KA, Wondisford FE, Korach KS, Woodruff TK, Greene GL. Sinkevicius KW, et al. Among authors: temple ka. Endocrinology. 2008 Jun;149(6):2970-9. doi: 10.1210/en.2007-1526. Epub 2008 Mar 13. Endocrinology. 2008. PMID: 18339713 Free PMC article.
31 results