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Identification of a key residue mediating bone morphogenetic protein (BMP)-6 resistance to noggin inhibition allows for engineered BMPs with superior agonist activity.
Song K, Krause C, Shi S, Patterson M, Suto R, Grgurevic L, Vukicevic S, van Dinther M, Falb D, Ten Dijke P, Alaoui-Ismaili MH. Song K, et al. Among authors: ten dijke p. J Biol Chem. 2010 Apr 16;285(16):12169-80. doi: 10.1074/jbc.M109.087197. Epub 2010 Jan 4. J Biol Chem. 2010. PMID: 20048150 Free PMC article.
BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo.
Buijs JT, Rentsch CA, van der Horst G, van Overveld PG, Wetterwald A, Schwaninger R, Henriquez NV, Ten Dijke P, Borovecki F, Markwalder R, Thalmann GN, Papapoulos SE, Pelger RC, Vukicevic S, Cecchini MG, Löwik CW, van der Pluijm G. Buijs JT, et al. Among authors: ten dijke p. Am J Pathol. 2007 Sep;171(3):1047-57. doi: 10.2353/ajpath.2007.070168. Am J Pathol. 2007. PMID: 17724140 Free PMC article.
Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer.
Buijs JT, Henriquez NV, van Overveld PG, van der Horst G, Que I, Schwaninger R, Rentsch C, Ten Dijke P, Cleton-Jansen AM, Driouch K, Lidereau R, Bachelier R, Vukicevic S, Clézardin P, Papapoulos SE, Cecchini MG, Löwik CW, van der Pluijm G. Buijs JT, et al. Among authors: ten dijke p. Cancer Res. 2007 Sep 15;67(18):8742-51. doi: 10.1158/0008-5472.CAN-06-2490. Cancer Res. 2007. PMID: 17875715 Free article.
463 results