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Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling.
Levy D, Kuo AJ, Chang Y, Schaefer U, Kitson C, Cheung P, Espejo A, Zee BM, Liu CL, Tangsombatvisit S, Tennen RI, Kuo AY, Tanjing S, Cheung R, Chua KF, Utz PJ, Shi X, Prinjha RK, Lee K, Garcia BA, Bedford MT, Tarakhovsky A, Cheng X, Gozani O. Levy D, et al. Among authors: tennen ri. Nat Immunol. 2011 Jan;12(1):29-36. doi: 10.1038/ni.1968. Epub 2010 Dec 5. Nat Immunol. 2011. PMID: 21131967 Free PMC article.
SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation.
Barber MF, Michishita-Kioi E, Xi Y, Tasselli L, Kioi M, Moqtaderi Z, Tennen RI, Paredes S, Young NL, Chen K, Struhl K, Garcia BA, Gozani O, Li W, Chua KF. Barber MF, et al. Among authors: tennen ri. Nature. 2012 Jul 5;487(7405):114-8. doi: 10.1038/nature11043. Nature. 2012. PMID: 22722849 Free PMC article.
Finding a target for resveratrol.
Tennen RI, Michishita-Kioi E, Chua KF. Tennen RI, et al. Cell. 2012 Feb 3;148(3):387-9. doi: 10.1016/j.cell.2012.01.032. Cell. 2012. PMID: 22304906 Free article.