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PRMT5-mediated regulation of developmental myelination.
Scaglione A, Patzig J, Liang J, Frawley R, Bok J, Mela A, Yattah C, Zhang J, Teo SX, Zhou T, Chen S, Bernstein E, Canoll P, Guccione E, Casaccia P. Scaglione A, et al. Among authors: teo sx. Nat Commun. 2018 Jul 19;9(1):2840. doi: 10.1038/s41467-018-04863-9. Nat Commun. 2018. PMID: 30026560 Free PMC article.
PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis.
Mzoughi S, Fong JY, Papadopoli D, Koh CM, Hulea L, Pigini P, Di Tullio F, Andreacchio G, Hoppe MM, Wollmann H, Low D, Caldez MJ, Peng Y, Torre D, Zhao JN, Uchenunu O, Varano G, Motofeanu CM, Lakshmanan M, Teo SX, Wun CM, Perini G, Tan SY, Ong CB, Al-Haddawi M, Rajarethinam R, Hue SS, Lim ST, Ong CK, Huang D, Ng SB, Bernstein E, Hasson D, Wee KB, Kaldis P, Jeyasekharan A, Dominguez-Sola D, Topisirovic I, Guccione E. Mzoughi S, et al. Among authors: teo sx. Nat Commun. 2020 Jul 14;11(1):3520. doi: 10.1038/s41467-020-17064-0. Nat Commun. 2020. PMID: 32665551 Free PMC article.
Antisense oligonucleotide-mediated MDM4 exon 6 skipping impairs tumor growth.
Dewaele M, Tabaglio T, Willekens K, Bezzi M, Teo SX, Low DH, Koh CM, Rambow F, Fiers M, Rogiers A, Radaelli E, Al-Haddawi M, Tan SY, Hermans E, Amant F, Yan H, Lakshmanan M, Koumar RC, Lim ST, Derheimer FA, Campbell RM, Bonday Z, Tergaonkar V, Shackleton M, Blattner C, Marine JC, Guccione E. Dewaele M, et al. Among authors: teo sx. J Clin Invest. 2016 Jan;126(1):68-84. doi: 10.1172/JCI82534. Epub 2015 Nov 23. J Clin Invest. 2016. PMID: 26595814 Free PMC article.
PRDM15 safeguards naive pluripotency by transcriptionally regulating WNT and MAPK-ERK signaling.
Mzoughi S, Zhang J, Hequet D, Teo SX, Fang H, Xing QR, Bezzi M, Seah MKY, Ong SLM, Shin EM, Wollmann H, Wong ESM, Al-Haddawi M, Stewart CL, Tergaonkar V, Loh YH, Dunn NR, Messerschmidt DM, Guccione E. Mzoughi S, et al. Among authors: teo sx. Nat Genet. 2017 Sep;49(9):1354-1363. doi: 10.1038/ng.3922. Epub 2017 Jul 24. Nat Genet. 2017. PMID: 28740264