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Calcitriol modulates epidermal tight junction barrier function in human keratinocytes.
Trujillo-Paez JV, Peng G, Le Thanh Nguyen H, Nakamura M, Umehara Y, Yue H, Ikutama R, Takahashi M, Ikeda S, Ogawa H, Okumura K, Niyonsaba F. Trujillo-Paez JV, et al. J Dermatol Sci. 2024 Feb 7:S0923-1811(24)00015-X. doi: 10.1016/j.jdermsci.2024.02.001. Online ahead of print. J Dermatol Sci. 2024. PMID: 38448341
TJ barrier function was assessed by the transepithelial electrical resistance (TER) assay. RESULTS: We demonstrated that calcitriol increased the expression levels of TJ-related proteins, including claudin-4, claudin-7, occludin, and zonula occludens (ZO)- 1. ...Indeed, we …
TJ barrier function was assessed by the transepithelial electrical resistance (TER) assay. RESULTS: We demonstrated that calcitriol i …
[Comparative characteristics of the complement system in patients with C3-glomerulopathy and atypical hemolytic uremic syndrome of chronic course who suffered an acute episode of thrombotic microangiopathy].
Yurova VA, Kozlovskaya NL, Bobrova LA, Kozlov LV, Andina SS, Demyanova KA. Yurova VA, et al. Ter Arkh. 2023 Aug 17;95(6):475-480. doi: 10.26442/00403660.2023.06.202269. Ter Arkh. 2023. PMID: 38158966 Russian.
AIM: To compare changes in the complement system in C3-glomerulopathy (C3-GP) and atypical hemolytic uremic syndrome (aHUS) after the relief of an acute episode of thrombotic microangiopathy. ...RESULTS: C3 and CH50 levels were within the reference range in b …
AIM: To compare changes in the complement system in C3-glomerulopathy (C3-GP) and atypical hemolytic uremic syndrome (aHUS) af …
[Clinical significance of uremic toxin indoxyl sulfate and inflammation in the development of vascular calcification and cardiovascular complications in stage C3-C5D chronic kidney disease].
Dzgoeva FU, Remizov OV, Goloeva VG, Ikoeva ZR. Dzgoeva FU, et al. Ter Arkh. 2023 Aug 17;95(6):468-474. doi: 10.26442/00403660.2023.06.202267. Ter Arkh. 2023. PMID: 38158965 Russian.
MATERIALS AND METHODS: One hundred fifteen patients aged 25 to 68 years with CKD stage C3-C5D were examined. Serum concentrations of IS, interleukin 6 (IL-6), tumor necrosis factor (TNF-alpha), troponin I, parathyroid hormone were determined by enzyme immunoassay using kit …
MATERIALS AND METHODS: One hundred fifteen patients aged 25 to 68 years with CKD stage C3-C5D were examined. Serum concentrations of …
Pioglitazone Protects Tubular Epithelial Cells during Kidney Fibrosis by Attenuating miRNA Dysregulation and Autophagy Dysfunction Induced by TGF-β.
Manzéger A, Garmaa G, Mózes MM, Hansmann G, Kökény G. Manzéger A, et al. Int J Mol Sci. 2023 Oct 24;24(21):15520. doi: 10.3390/ijms242115520. Int J Mol Sci. 2023. PMID: 37958504 Free PMC article.

These were accompanied by 5-fold, 3-fold, 12-fold, and 2-fold suppression (p < 0.05) of renal Ccl2, Il6, C3, and Lgals3 mRNA expression, respectively. Our results implicate that pioglitazone counteracts multiple pro-fibrotic processes in the kidney, including autophagy

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These were accompanied by 5-fold, 3-fold, 12-fold, and 2-fold suppression (p < 0.05) of renal Ccl2, Il6, C3, and Lgals3 mRNA expre

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HK-2 cell response to TGF-β highly depends on cell culture medium formulations.
Garmaa G, Manzéger A, Haghighi S, Kökény G. Garmaa G, et al. Histochem Cell Biol. 2024 Jan;161(1):69-79. doi: 10.1007/s00418-023-02237-x. Epub 2023 Sep 26. Histochem Cell Biol. 2024. PMID: 37752256 Free PMC article.
Interestingly, TGF-beta1 treatment either increased or decreased EGR1, FN, IL6 and C3 gene expression, depending on medium formulations. The cell morphology was slightly affected, but immunoblots revealed TGFB1 and vimentin protein overexpression in all media. ...
Interestingly, TGF-beta1 treatment either increased or decreased EGR1, FN, IL6 and C3 gene expression, depending on medium formulatio …
[Remissions and progression of C3 glomerulopathy].
Karunnaya AV, Dobronravov VA. Karunnaya AV, et al. Ter Arkh. 2022 Aug 4;94(6):718-724. doi: 10.26442/00403660.2022.06.201564. Ter Arkh. 2022. PMID: 36286847 Russian.
AIM: To analyze the outcomes of C3-glomerulopathy (C3-GP) and determine the associated factors. MATERIALS AND METHODS: A retrospective single-center study included 60 patients with newly diagnosed C3-GP (with primary C3-GP pC3-GP 82%). Of these, 48 (80 …
AIM: To analyze the outcomes of C3-glomerulopathy (C3-GP) and determine the associated factors. MATERIALS AND METHODS: A retro …
Stable carbon and nitrogen isotopes identify nuanced dietary changes from the Bronze and Iron Ages on the Great Hungarian Plain.
McCall A, Gamarra B, Carlson KSD, Bernert Z, Cséki A, Csengeri P, Domboróczki L, Endrődi A, Hellebrandt M, Horváth A, Király Á, Kiss K, Koós J, Kovács P, Köhler K, Szolnoki L, Zoffmann ZK, Sirak K, Szeniczey T, Dani J, Hajdu T, Pinhasi R. McCall A, et al. Sci Rep. 2022 Oct 10;12(1):16982. doi: 10.1038/s41598-022-21138-y. Sci Rep. 2022. PMID: 36217009 Free PMC article.
Dabigatran and Wet AMD, Results From Retinal Pigment Epithelial Cell Monolayers, the Mouse Model of Choroidal Neovascularization, and Patients From the Medicare Data Base.
Akter T, Annamalai B, Obert E, Simpson KN, Rohrer B. Akter T, et al. Front Immunol. 2022 Jun 17;13:896274. doi: 10.3389/fimmu.2022.896274. eCollection 2022. Front Immunol. 2022. PMID: 35784301 Free PMC article.
ARPE-19 cells grown as mature monolayers were analyzed for thrombin effects on barrier function (transepithelial resistance; TER) and downstream signaling (complement activation, expression of connective tissue growth factor (CTGF), and secretion of vascular endothelial gr …
ARPE-19 cells grown as mature monolayers were analyzed for thrombin effects on barrier function (transepithelial resistance; TER) and …
109 results