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Alkylpurine-DNA-N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients.
J Clin Invest. 2012 Jan;122(1):253-66. doi: 10.1172/JCI59334. Epub 2011 Dec 12.
J Clin Invest. 2012.
PMID: 22156195
Free PMC article.
ATM regulates 3-methylpurine-DNA glycosylase and promotes therapeutic resistance to alkylating agents.
Agnihotri S, Burrell K, Buczkowicz P, Remke M, Golbourn B, Chornenkyy Y, Gajadhar A, Fernandez NA, Clarke ID, Barszczyk MS, Pajovic S, Ternamian C, Head R, Sabha N, Sobol RW, Taylor MD, Rutka JT, Jones C, Dirks PB, Zadeh G, Hawkins C.
Agnihotri S, et al. Among authors: ternamian c.
Cancer Discov. 2014 Oct;4(10):1198-213. doi: 10.1158/2159-8290.CD-14-0157. Epub 2014 Aug 6.
Cancer Discov. 2014.
PMID: 25100205
Free PMC article.
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