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2002 2
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2004 5
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305 results

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Page 1
Positive Tetrahydrocurcumin-Associated Brain-Related Metabolomic Implications.
Josifovska S, Panov S, Hadzi-Petrushev N, Mitrokhin V, Kamkin A, Stojchevski R, Avtanski D, Mladenov M. Josifovska S, et al. Molecules. 2023 Apr 26;28(9):3734. doi: 10.3390/molecules28093734. Molecules. 2023. PMID: 37175144 Free PMC article. Review.
Tetrahydrocurcumin (THC) is a metabolite of curcumin (CUR). It shares many of CUR's beneficial biological activities in addition to being more water-soluble, chemically stable, and bioavailable compared to CUR. ...
Tetrahydrocurcumin (THC) is a metabolite of curcumin (CUR). It shares many of CUR's beneficial biological activities in addition to b
Tetrahydrocurcumin-Related Vascular Protection: An Overview of the Findings from Animal Disease Models.
Zhang L, Li C, Wang S, Avtanski D, Hadzi-Petrushev N, Mitrokhin V, Mladenov M, Wang F. Zhang L, et al. Molecules. 2022 Aug 10;27(16):5100. doi: 10.3390/molecules27165100. Molecules. 2022. PMID: 36014335 Free PMC article. Review.
Tetrahydrocurcumin (THC), one of the major metabolites of CUR, possesses several CUR-like pharmacological effects; however, its mechanisms of action are largely unknown. ...
Tetrahydrocurcumin (THC), one of the major metabolites of CUR, possesses several CUR-like pharmacological effects; however, its mecha
The Cancer Chemopreventive and Therapeutic Potential of Tetrahydrocurcumin.
Lai CS, Ho CT, Pan MH. Lai CS, et al. Biomolecules. 2020 May 29;10(6):831. doi: 10.3390/biom10060831. Biomolecules. 2020. PMID: 32486019 Free PMC article. Review.
Despite the pharmacological similarities between tetrahydrocurcumin and curcumin, the structure of tetrahydrocurcumin determines its distinct and specific molecular mechanism, thus making it a potential candidate for the prevention and treatment of cancers. ...This …
Despite the pharmacological similarities between tetrahydrocurcumin and curcumin, the structure of tetrahydrocurcumin determin …
Curcumin Metabolite Tetrahydrocurcumin in the Treatment of Eye Diseases.
Kao YW, Hsu SK, Chen JY, Lin IL, Chen KJ, Lee PY, Ng HS, Chiu CC, Cheng KC. Kao YW, et al. Int J Mol Sci. 2020 Dec 28;22(1):212. doi: 10.3390/ijms22010212. Int J Mol Sci. 2020. PMID: 33379248 Free PMC article. Review.
Recent studies focus on the protective role of plasma tetrahydrocurcumin (THC), a main metabolite of curcumin, against tumors and chronic inflammatory diseases. ...
Recent studies focus on the protective role of plasma tetrahydrocurcumin (THC), a main metabolite of curcumin, against tumors and chr …
Tetrahydrocurcumin ameliorates postinfarction cardiac dysfunction and remodeling by inhibiting oxidative stress and preserving mitochondrial function via SIRT3 signaling pathway.
Zhang B, Yang J, Li X, Zhu H, Sun J, Jiang L, Xue C, Zhang L, Xu C, Xing S, Jin Z, Liu J, Yu S, Duan W. Zhang B, et al. Phytomedicine. 2023 Dec;121:155127. doi: 10.1016/j.phymed.2023.155127. Epub 2023 Oct 2. Phytomedicine. 2023. PMID: 37812853 Free article.
Persistent myocardial ischemia increases oxidative stress and impairs mitochondrial function, contributing significantly to postinfarction cardiac dysfunction and remodeling, and the subsequent progression to heart failure (HF). Tetrahydrocurcumin (THC), isolated from the …
Persistent myocardial ischemia increases oxidative stress and impairs mitochondrial function, contributing significantly to postinfarction c …
The role of tetrahydrocurcumin in disease prevention and treatment.
Zhou M, Li R, Hua H, Dai Y, Yin Z, Li L, Zeng J, Yang M, Zhao J, Tan R. Zhou M, et al. Food Funct. 2024 Jun 5. doi: 10.1039/d3fo05739a. Online ahead of print. Food Funct. 2024. PMID: 38836693 Review.
However, the pharmacological application of curcumin is limited due to its poor systemic bioavailability. As a major active metabolite of curcumin, tetrahydrocurcumin (THC) has higher bioavailability and stability than curcumin. ...
However, the pharmacological application of curcumin is limited due to its poor systemic bioavailability. As a major active metabolite of cu …
Tetrahydrocurcumin improves lipopolysaccharide-induced myocardial dysfunction by inhibiting oxidative stress and inflammation via JNK/ERK signaling pathway regulation.
Zhu H, Zhang L, Jia H, Xu L, Cao Y, Zhai M, Li K, Xia L, Jiang L, Li X, Zhou Y, Liu J, Yu S, Duan W. Zhu H, et al. Phytomedicine. 2022 Sep;104:154283. doi: 10.1016/j.phymed.2022.154283. Epub 2022 Jun 18. Phytomedicine. 2022. PMID: 35779282 Free article.
BACKGROUND: Acute myocardial dysfunction in patients with sepsis is attributed to oxidative stress, inflammation, and cardiomyocyte loss; however, specific drugs for its prevention are still lacking. Tetrahydrocurcumin (THC) has been proven to contribute to the prevention …
BACKGROUND: Acute myocardial dysfunction in patients with sepsis is attributed to oxidative stress, inflammation, and cardiomyocyte loss; ho …
Antibacterial and Antiviral Properties of Tetrahydrocurcumin-Based Formulations: An Overview of Their Metabolism in Different Microbiotic Compartments.
Atanasova-Panchevska N, Stojchevski R, Hadzi-Petrushev N, Mitrokhin V, Avtanski D, Mladenov M. Atanasova-Panchevska N, et al. Life (Basel). 2022 Oct 26;12(11):1708. doi: 10.3390/life12111708. Life (Basel). 2022. PMID: 36362863 Free PMC article. Review.
In this review, the basic metabolic characteristics of the curcuminoid tetrahydrocurcumin (THC) at the level of the intestinal microbiota were addressed. ...
In this review, the basic metabolic characteristics of the curcuminoid tetrahydrocurcumin (THC) at the level of the intestinal microb …
Tetrahydrocurcumin Ameliorates Acute Hypobaric Hypoxia-Induced Cognitive Impairment in Mice.
Ma X, Pan Y, Xue Y, Li Y, Zhang Y, Zhao Y, Xiong X, Wang J, Yang Z. Ma X, et al. High Alt Med Biol. 2022 Sep;23(3):264-272. doi: 10.1089/ham.2021.0061. Epub 2022 Jun 20. High Alt Med Biol. 2022. PMID: 35723652
Ma, Xuexinyu, Yang Pan, Yuye Xue, Yao Li, Yan Zhang, Yani Zhao, Xingzhao Xiong, Jianbo Wang, and Zhifu Yang. Tetrahydrocurcumin ameliorates acute hypobaric hypoxia-induced cognitive impairment in mice. ...Background: Hypobaric hypoxia (HH) impairs spatial learning and incr …
Ma, Xuexinyu, Yang Pan, Yuye Xue, Yao Li, Yan Zhang, Yani Zhao, Xingzhao Xiong, Jianbo Wang, and Zhifu Yang. Tetrahydrocurcumin ameli …
Chemopreventative effects of tetrahydrocurcumin on human diseases.
Wu JC, Tsai ML, Lai CS, Wang YJ, Ho CT, Pan MH. Wu JC, et al. Food Funct. 2014 Jan;5(1):12-7. doi: 10.1039/c3fo60370a. Food Funct. 2014. PMID: 24220621 Review.
Chemoprevention is a relatively new and promising strategy to prevent human degenerative diseases, including cancer, and is defined as the use of natural dietary compounds and/or synthetic substances to block, inhibit, reverse, or retard the progress of human diseases. Tetrahy
Chemoprevention is a relatively new and promising strategy to prevent human degenerative diseases, including cancer, and is defined as the u …
305 results