Neoclerodane diterpenoids from Teucrium montbretii subsp. libanoticum and their absolute configuration

J Nat Prod. 2002 Feb;65(2):142-6. doi: 10.1021/np010303m.

Abstract

From the aerial parts of Teucrium montbretii subsp. libanoticum 10 neoclerodane diterpenoids were isolated. Three of them are new [3beta-hydroxyteubutilin A (1), 12-epi-montanin G (2), 20-epi-3,20-di-O-deacetylteupyreinidin (3)], whereas the other seven, namely, 6-ketoteuscordin (4), teuscordinon (5), 6beta-hydroxyteuscordin (6), montanin D (7), 3,20-di-O-deacetylteupyreinidin (8), montanin G (9), and 3-O-deacetylteugracilin A (10), are previously known structures. The structures of 1-3 were determined by spectral and chemical methods.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromatography, Thin Layer
  • Diterpenes / chemistry
  • Diterpenes / isolation & purification*
  • Lamiaceae / chemistry*
  • Lamiaceae / classification
  • Lebanon
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plants, Medicinal / chemistry*
  • Spectrophotometry, Infrared
  • Stereoisomerism

Substances

  • 12-epi-montanin G
  • 20-epi-3,20-di-O-deacetylteupyreinidin
  • 3-hydroxyteubutilin A
  • Diterpenes
  • teuscordonin
  • Montanin