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7,638 results

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Page 1
Pivotal Evaluation of Novel Dedicated Venous Stent for Iliofemoral Venous Obstruction: A Prospective Cohort Study.
Ma X, Yang J, Yin M, Liu F, Wu W, Li Y, Qin X, Zhang L, Xiao Z, Xu H, Zhu Y, Wang L, Zhang J, Fan L, Dai X, Yang M, Chen B, Hao B, Lin S, Liao B, Fu W, Guo W. Ma X, et al. J Endovasc Ther. 2024 Apr 15:15266028241245325. doi: 10.1177/15266028241245325. Online ahead of print. J Endovasc Ther. 2024. PMID: 38616626
There were 3 early major adverse events (1 intracerebral hemorrhage and 2 stent thrombosis events related to anticoagulation therapy), and 7 late major adverse events (1 cardiovascular death, 1 intracranial hemorrhage with uncontrolled hypertension, and 5 in-stent restenos …
There were 3 early major adverse events (1 intracerebral hemorrhage and 2 stent thrombosis events related to anticoagulation therapy) …
A Rare Case of Postpartum Paraplegia: A Case Report.
Kumar D, Kaur G, Chawla SK, Singh H. Kumar D, et al. J Pharm Bioallied Sci. 2024 Feb;16(Suppl 1):S979-S982. doi: 10.4103/jpbs.jpbs_915_23. Epub 2024 Feb 29. J Pharm Bioallied Sci. 2024. PMID: 38595578 Free PMC article.
Treatment included anticoagulant therapy, high-dose steroid therapy, and antihypertensive drugs, emphasizing the crucial importance of inter-disciplinary care in handling such complex situations. Even if the patient's symptoms have partially improved, their c …
Treatment included anticoagulant therapy, high-dose steroid therapy, and antihypertensive drugs, emphasizing the crucial impor …
[Low disease activity and remission status of systemic lupus erythematosus in a real-world study].
Ren L, Zhao C, Zhao Y, Zhou H, Zhang L, Wang Y, Shen L, Fan W, Li Y, Li X, Wang J, Cheng Y, Peng J, Zhao X, Shao M, Li R. Ren L, et al. Beijing Da Xue Xue Bao Yi Xue Ban. 2024 Apr 18;56(2):273-278. doi: 10.19723/j.issn.1671-167X.2024.02.011. Beijing Da Xue Xue Bao Yi Xue Ban. 2024. PMID: 38595244 Free article. Chinese.
Patients who received hydroxychloroquine for more than 12 months or immunosuppressant therapy for no less than 6 months earned higher rates of LLDAS and DORIS remission. The results of Logistic regression analysis showed that increased ESR, positive anti-dsDNA antibodies, …
Patients who received hydroxychloroquine for more than 12 months or immunosuppressant therapy for no less than 6 months earned higher …
Hemolysis events in the Phase 3 PEGASUS study of pegcetacoplan in patients with paroxysmal nocturnal hemoglobinuria.
Peffault de Latour R, Griffin M, Kelly RJ, Szer J, de Castro C, Horneff R, Tan L, Yeh MM, Panse JP. Peffault de Latour R, et al. Blood Adv. 2024 Apr 9:bloodadvances.2024012672. doi: 10.1182/bloodadvances.2024012672. Online ahead of print. Blood Adv. 2024. PMID: 38593241
Patients with paroxysmal nocturnal hemoglobinuria (PNH) experience complement-mediated intravascular hemolysis leading to anemia, fatigue, and potentially life-threatening thrombotic complications. Pegcetacoplan, a C3 inhibitor, demonstrated sustained improvements in hemat …
Patients with paroxysmal nocturnal hemoglobinuria (PNH) experience complement-mediated intravascular hemolysis leading to anemia, fatigue, a …
Ketamine's mechanism of action with an emphasis on neuroimmune regulation: can the complement system complement ketamine's antidepressant effects?
Quintanilla B, Zarate CA Jr, Pillai A. Quintanilla B, et al. Mol Psychiatry. 2024 Apr 4. doi: 10.1038/s41380-024-02507-7. Online ahead of print. Mol Psychiatry. 2024. PMID: 38575806 Review.
Many research endeavors have sought to identify ketamine's mechanism of action in mood disorders; while many studies have focused on ketamine's role in glutamatergic modulation, several studies have implicated its role in regulating neuroinflammation. ...Given the r …
Many research endeavors have sought to identify ketamine's mechanism of action in mood disorders; while many studies have focused on …
Safety and Efficacy of Pegcetacoplan in Adult Patients with Paroxysmal Nocturnal Hemoglobinuria over 48 Weeks: 307 Open-Label Extension Study.
Patriquin CJ, Bogdanovic A, Griffin M, Kelly RJ, Maciejewski JP, Mulherin B, Peffault de Latour R, Röth A, Selvaratnam V, Szer J, Al-Adhami M, Horneff R, Tan L, Yeh M, Panse J. Patriquin CJ, et al. Adv Ther. 2024 Apr 4. doi: 10.1007/s12325-024-02827-8. Online ahead of print. Adv Ther. 2024. PMID: 38573482
INTRODUCTION: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, life-threatening disease characterized by complement-mediated hemolysis and thrombosis. Pegcetacoplan, the first targeted complement component 3 (C3) PNH therapy, was safe and efficacious in treatmen …
INTRODUCTION: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, life-threatening disease characterized by complement-mediated hemolysis a …
Conservative Management of Trigeminal Neuralgia and Degenerative Cervical Myelopathy: A Case Report.
Chu EC, Rissardo JP. Chu EC, et al. Cureus. 2024 Feb 29;16(2):e55274. doi: 10.7759/cureus.55274. eCollection 2024 Feb. Cureus. 2024. PMID: 38558660 Free PMC article.
It is hypothesized that degenerative cervical myelopathy (DCM) may induce or exacerbate trigeminal neuralgia (TN) through mechanisms such as direct compression of the spinal trigeminal tract, inflammation, or vascular issues, leading to ischemia within cervical segments C3 …
It is hypothesized that degenerative cervical myelopathy (DCM) may induce or exacerbate trigeminal neuralgia (TN) through mechanisms such as …
A Rare Presentation of Polyarteritis Nodosa (PAN).
Enabi J, Shah K, Kondakindi H, Mukkera S. Enabi J, et al. Cureus. 2024 Feb 28;16(2):e55143. doi: 10.7759/cureus.55143. eCollection 2024 Feb. Cureus. 2024. PMID: 38558645 Free PMC article.
Due to the severity of PAN, therapy with IV cyclophosphamide therapy 15 mg/kg once every two weeks for three doses was initiated, followed by 15 mg/kg once every three weeks for three to six months (in combination with glucocorticoids prednisone 1 mg/kg body weight …
Due to the severity of PAN, therapy with IV cyclophosphamide therapy 15 mg/kg once every two weeks for three doses was initiat …
Effect of total flavonoids of Dracocephalum moldavica L. On neuroinflammation in Alzheimer's disease model amyloid-beta (Abeta1-42)-peptide-induced astrocyte activation.
Ren W, Yan XS, Fan JC, Huo DS, Wang XX, Jia JX, Yang ZJ. Ren W, et al. J Toxicol Environ Health A. 2024 May 18;87(10):436-447. doi: 10.1080/15287394.2024.2336570. Epub 2024 Apr 1. J Toxicol Environ Health A. 2024. PMID: 38557424
One of the main pathological features noted in Alzheimer's disease (AD) is the presence of plagues of aggregated beta-amyloid (Abeta1-42)-peptides. ...Therefore, TFDM similar to donepezil inhibited inflammatory secretion in reactive astrocytes, suggesting that TFDM may be …
One of the main pathological features noted in Alzheimer's disease (AD) is the presence of plagues of aggregated beta-amyloid (Abeta1 …
C1q and HBHA-specific IL-13 levels as surrogate plasma biomarkers for monitoring tuberculosis treatment efficacy: a cross-sectional cohort study in Paraguay.
Russomando G, Sanabria D, Díaz Acosta CC, Rojas L, Franco L, Arenas R, Delogu G, Ndiaye MDB, Bayaa R, Rakotosamimanana N, Goletti D, Hoffmann J. Russomando G, et al. Front Immunol. 2024 Mar 13;15:1308015. doi: 10.3389/fimmu.2024.1308015. eCollection 2024. Front Immunol. 2024. PMID: 38545118 Free PMC article.
At each timepoint plasma levels of IFN-y, 17 pro- and anti-inflammatory cytokines/chemokines and complement factors C1q, C3 and C4 were assessed in unstimulated and Mtb-specific stimulated whole blood samples using QuantiFERON-TB gold plus and recombinant Mycobacterium sme …
At each timepoint plasma levels of IFN-y, 17 pro- and anti-inflammatory cytokines/chemokines and complement factors C1q, C3 and C4 we …
7,638 results