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The relation of S100beta and metabolic and endocrine responses to acute fetal hypoxemia.
Thakor AS, Gazzolo D, Frulio R, Giussani DA. Thakor AS, et al. Front Biosci (Elite Ed). 2010 Jan 1;2:59-67. doi: 10.2741/e66. Front Biosci (Elite Ed). 2010. PMID: 20036854
Elevations in S100beta protein in umbilical cord blood have been proposed as a reproducible marker of fetal stress, leading to cell damage within the central nervous system. ...
Elevations in S100beta protein in umbilical cord blood have been proposed as a reproducible marker of fetal stress, leading to cell d …
Fetal in vivo continuous cardiovascular function during chronic hypoxia.
Allison BJ, Brain KL, Niu Y, Kane AD, Herrera EA, Thakor AS, Botting KJ, Cross CM, Itani N, Skeffington KL, Beck C, Giussani DA. Allison BJ, et al. J Physiol. 2016 Mar 1;594(5):1247-64. doi: 10.1113/JP271091. J Physiol. 2016. PMID: 26926316 Free PMC article.
We also created a wireless data acquisition system able to record fetal blood flow signals in addition to fetal blood pressure and heart rate from free moving ewes as the hypoxic pregnancy is developing. ...
We also created a wireless data acquisition system able to record fetal blood flow signals in addition to fetal blood pressure and heart rat …
A role for xanthine oxidase in the control of fetal cardiovascular function in late gestation sheep.
Herrera EA, Kane AD, Hansell JA, Thakor AS, Allison BJ, Niu Y, Giussani DA. Herrera EA, et al. J Physiol. 2012 Apr 15;590(8):1825-37. doi: 10.1113/jphysiol.2011.224576. Epub 2012 Feb 13. J Physiol. 2012. PMID: 22331413 Free PMC article.
Redox modulation of the fetal cardiovascular defence to hypoxaemia.
Thakor AS, Richter HG, Kane AD, Dunster C, Kelly FJ, Poston L, Giussani DA. Thakor AS, et al. J Physiol. 2010 Nov 1;588(Pt 21):4235-47. doi: 10.1113/jphysiol.2010.196402. J Physiol. 2010. PMID: 20807788 Free PMC article.
Effects of acute acidemia on the fetal cardiovascular defense to acute hypoxemia.
Thakor AS, Giussani DA. Thakor AS, et al. Am J Physiol Regul Integr Comp Physiol. 2009 Jan;296(1):R90-9. doi: 10.1152/ajpregu.90689.2008. Epub 2008 Oct 15. Am J Physiol Regul Integr Comp Physiol. 2009. PMID: 18922958
Role of nitric oxide in mediating in vivo vascular responses to calcitonin gene-related peptide in essential and peripheral circulations in the fetus.
Thakor AS, Giussani DA. Thakor AS, et al. Circulation. 2005 Oct 18;112(16):2510-6. doi: 10.1161/CIRCULATIONAHA.105.562546. Epub 2005 Oct 10. Circulation. 2005. PMID: 16216959
However, whether CGRP acts as a vasodilator in the fetus in vivo and whether this effect is mediated via NO have been addressed only minimally. ...
However, whether CGRP acts as a vasodilator in the fetus in vivo and whether this effect is mediated via NO have been addressed only …
Calcitonin gene-related peptide antagonism attenuates the haemodynamic and glycaemic responses to acute hypoxaemia in the late gestation sheep fetus.
Thakor AS, Bloomfield MR, Patterson M, Giussani DA. Thakor AS, et al. J Physiol. 2005 Jul 15;566(Pt 2):587-97. doi: 10.1113/jphysiol.2005.085431. Epub 2005 Apr 28. J Physiol. 2005. PMID: 15860534 Free PMC article.
Calcitonin gene-related peptide contributes to the umbilical haemodynamic defence response to acute hypoxaemia.
Thakor AS, Giussani DA. Thakor AS, et al. J Physiol. 2005 Feb 15;563(Pt 1):309-17. doi: 10.1113/jphysiol.2004.077024. Epub 2004 Dec 20. J Physiol. 2005. PMID: 15611032 Free PMC article.
The fetal defence to hypoxaemia involves a redistribution of blood flow away from peripheral circulations towards essential vascular beds, such as the umbilical, cerebral, myocardial and adrenal circulations. ...
The fetal defence to hypoxaemia involves a redistribution of blood flow away from peripheral circulations towards essential vascular beds, s …
Melatonin modulates the fetal cardiovascular defense response to acute hypoxia.
Thakor AS, Allison BJ, Niu Y, Botting KJ, Serón-Ferré M, Herrera EA, Giussani DA. Thakor AS, et al. J Pineal Res. 2015 Aug;59(1):80-90. doi: 10.1111/jpi.12242. Epub 2015 May 13. J Pineal Res. 2015. PMID: 25908097 Free PMC article.
However, the effects of melatonin on the fetal defense to acute hypoxia, such as that which may occur during labor, remain unknown. ...The effects of melatonin involved NO-dependent mechanisms as the responses were reverted by fetal treatment with the NO clamp. ...
However, the effects of melatonin on the fetal defense to acute hypoxia, such as that which may occur during labor, remain unknown. . …
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