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Limited role of free TDP-43 as a diagnostic tool in neurodegenerative diseases.
Feneberg E, Steinacker P, Lehnert S, Schneider A, Walther P, Thal DR, Linsenmeier M, Ludolph AC, Otto M. Feneberg E, et al. Among authors: thal dr. Amyotroph Lateral Scler Frontotemporal Degener. 2014 Sep;15(5-6):351-6. doi: 10.3109/21678421.2014.905606. Epub 2014 May 16. Amyotroph Lateral Scler Frontotemporal Degener. 2014. PMID: 24834468
Genetic variants in PSEN2 and correlation to CSF β-amyloid42 levels in AD.
Lebedeva E, Stingl JC, Thal DR, Ghebremedhin E, Strauss J, Özer E, Bertram L, von Einem B, Tumani H, Otto M, Riepe MW, Högel J, Ludolph AC, von Arnim CA. Lebedeva E, et al. Among authors: thal dr. Neurobiol Aging. 2012 Jan;33(1):201.e9-18. doi: 10.1016/j.neurobiolaging.2010.07.017. Epub 2010 Sep 18. Neurobiol Aging. 2012. PMID: 20850903
Chitinase enzyme activity in CSF is a powerful biomarker of Alzheimer disease.
Watabe-Rudolph M, Song Z, Lausser L, Schnack C, Begus-Nahrmann Y, Scheithauer MO, Rettinger G, Otto M, Tumani H, Thal DR, Attems J, Jellinger KA, Kestler HA, von Arnim CA, Rudolph KL. Watabe-Rudolph M, et al. Among authors: thal dr. Neurology. 2012 Feb 21;78(8):569-77. doi: 10.1212/WNL.0b013e318247caa1. Epub 2012 Feb 8. Neurology. 2012. PMID: 22323746
Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization.
Eschbach J, von Einem B, Müller K, Bayer H, Scheffold A, Morrison BE, Rudolph KL, Thal DR, Witting A, Weydt P, Otto M, Fauler M, Liss B, McLean PJ, Spada AR, Ludolph AC, Weishaupt JH, Danzer KM. Eschbach J, et al. Among authors: thal dr. Ann Neurol. 2015 Jan;77(1):15-32. doi: 10.1002/ana.24294. Epub 2014 Dec 19. Ann Neurol. 2015. PMID: 25363075 Free PMC article.
Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia.
Freischmidt A, Wieland T, Richter B, Ruf W, Schaeffer V, Müller K, Marroquin N, Nordin F, Hübers A, Weydt P, Pinto S, Press R, Millecamps S, Molko N, Bernard E, Desnuelle C, Soriani MH, Dorst J, Graf E, Nordström U, Feiler MS, Putz S, Boeckers TM, Meyer T, Winkler AS, Winkelman J, de Carvalho M, Thal DR, Otto M, Brännström T, Volk AE, Kursula P, Danzer KM, Lichtner P, Dikic I, Meitinger T, Ludolph AC, Strom TM, Andersen PM, Weishaupt JH. Freischmidt A, et al. Among authors: thal dr. Nat Neurosci. 2015 May;18(5):631-6. doi: 10.1038/nn.4000. Epub 2015 Mar 24. Nat Neurosci. 2015. PMID: 25803835
Thiamine deficiency in amyotrophic lateral sclerosis.
Jesse S, Thal DR, Ludolph AC. Jesse S, et al. Among authors: thal dr. J Neurol Neurosurg Psychiatry. 2015 Oct;86(10):1166-8. doi: 10.1136/jnnp-2014-309435. Epub 2015 Apr 21. J Neurol Neurosurg Psychiatry. 2015. PMID: 25901033 No abstract available.
TDP-43 is intercellularly transmitted across axon terminals.
Feiler MS, Strobel B, Freischmidt A, Helferich AM, Kappel J, Brewer BM, Li D, Thal DR, Walther P, Ludolph AC, Danzer KM, Weishaupt JH. Feiler MS, et al. Among authors: thal dr. J Cell Biol. 2015 Nov 23;211(4):897-911. doi: 10.1083/jcb.201504057. J Cell Biol. 2015. PMID: 26598621 Free PMC article.
240 results