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Trichuris suis secrete products that reduce disease severity in a multiple sclerosis model.

Hansen CS, Hasseldam H, Bacher IH, Thamsborg SM, Johansen FF, Kringel H. Hansen CS, et al. Among authors: thamsborg sm. Acta Parasitol. 2017 Mar 1;62(1):22-28. doi: 10.1515/ap-2017-0002. Acta Parasitol. 2017. PMID: 28030334

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Trichuris suis ova therapy for allergic rhinitis does not affect allergen-specific cytokine responses despite a parasite-specific cytokine response.

Bourke CD, Mutapi F, Nausch N, Photiou DM, Poulsen LK, Kristensen B, Arnved J, Rønborg S, Roepstorff A, Thamsborg S, Kapel C, Melbye M, Bager P. Bourke CD, et al. Clin Exp Allergy. 2012 Nov;42(11):1582-95. doi: 10.1111/j.1365-2222.2012.04063.x. Clin Exp Allergy. 2012. PMID: 23106658 Clinical Trial.

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Genome and transcriptome of the porcine whipworm Trichuris suis.

Jex AR, Nejsum P, Schwarz EM, Hu L, Young ND, Hall RS, Korhonen PK, Liao S, Thamsborg S, Xia J, Xu P, Wang S, Scheerlinck JP, Hofmann A, Sternberg PW, Wang J, Gasser RB. Jex AR, et al. Nat Genet. 2014 Jul;46(7):701-6. doi: 10.1038/ng.3012. Epub 2014 Jun 15. Nat Genet. 2014. PMID: 24929829 Free PMC article.

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Trichuris suis ova therapy in relapsing multiple sclerosis is safe but without signals of beneficial effect.

Voldsgaard A, Bager P, Garde E, Åkeson P, Leffers AM, Madsen CG, Kapel C, Roepstorff A, Thamsborg SM, Melbye M, Siebner H, Søndergaard HB, Sellebjerg F, Sørensen PS. Voldsgaard A, et al. Among authors: thamsborg sm. Mult Scler. 2015 Nov;21(13):1723-9. doi: 10.1177/1352458514568173. Epub 2015 Feb 19. Mult Scler. 2015. PMID: 25698173 Clinical Trial.

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Co-operative suppression of inflammatory responses in human dendritic cells by plant proanthocyanidins and products from the parasitic nematode Trichuris suis.

Williams AR, Klaver EJ, Laan LC, Ramsay A, Fryganas C, Difborg R, Kringel H, Reed JD, Mueller-Harvey I, Skov S, van Die I, Thamsborg SM. Williams AR, et al. Among authors: thamsborg sm. Immunology. 2017 Mar;150(3):312-328. doi: 10.1111/imm.12687. Epub 2016 Nov 30. Immunology. 2017. PMID: 27905107 Free PMC article.

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The transcriptome of Trichuris suis--first molecular insights into a parasite with curative properties for key immune diseases of humans.

Cantacessi C, Young ND, Nejsum P, Jex AR, Campbell BE, Hall RS, Thamsborg SM, Scheerlinck JP, Gasser RB. Cantacessi C, et al. Among authors: thamsborg sm. PLoS One. 2011;6(8):e23590. doi: 10.1371/journal.pone.0023590. Epub 2011 Aug 24. PLoS One. 2011. PMID: 21887281 Free PMC article.

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Temperature dependent embryonic development of Trichuris suis eggs in a medicinal raw material.

Vejzagić N, Kringel H, Bruun JM, Roepstorff A, Thamsborg SM, Grossi AB, Kapel CM. Vejzagić N, et al. Among authors: thamsborg sm. Vet Parasitol. 2016 Jan 15;215:48-57. doi: 10.1016/j.vetpar.2015.10.031. Epub 2015 Nov 27. Vet Parasitol. 2016. PMID: 26790737

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In vitro hatching of Trichuris suis eggs.

Vejzagić N, Thamsborg SM, Kringel H, Roepstorff A, Bruun JM, Kapel CM. Vejzagić N, et al. Among authors: thamsborg sm. Parasitol Res. 2015 Jul;114(7):2705-14. doi: 10.1007/s00436-015-4476-1. Epub 2015 May 27. Parasitol Res. 2015. PMID: 26008635

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Trichuris suis ova therapy for allergic rhinitis: a randomized, double-blind, placebo-controlled clinical trial.

Bager P, Arnved J, Rønborg S, Wohlfahrt J, Poulsen LK, Westergaard T, Petersen HW, Kristensen B, Thamsborg S, Roepstorff A, Kapel C, Melbye M. Bager P, et al. J Allergy Clin Immunol. 2010 Jan;125(1):123-30.e1-3. doi: 10.1016/j.jaci.2009.08.006. Epub 2009 Oct 3. J Allergy Clin Immunol. 2010. PMID: 19800680 Clinical Trial.

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The whipworm (Trichuris suis) secretes prostaglandin E2 to suppress proinflammatory properties in human dendritic cells.

Laan LC, Williams AR, Stavenhagen K, Giera M, Kooij G, Vlasakov I, Kalay H, Kringel H, Nejsum P, Thamsborg SM, Wuhrer M, Dijkstra CD, Cummings RD, van Die I. Laan LC, et al. Among authors: thamsborg sm. FASEB J. 2017 Feb;31(2):719-731. doi: 10.1096/fj.201600841R. Epub 2016 Nov 2. FASEB J. 2017. PMID: 27806992 Free PMC article.

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