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Influenza vaccine based on AS03-adjuvanted chimeric HA induces long-lived stalk-specific plasma cells in bone marrow and lymph nodes of nonhuman primates.
Akhtar A, Styles TM, Gu C, León AN, Tharp GK, Stokdyk K, Abbad A, Hirst C, Strohmeier S, Neumann G, Richey ST, Ferguson JA, Mala U, Ahmed H, Han J, Carreño JM, Davis CW, Antia R, Palese P, Ward AB, Kawaoka Y, Krammer F, Ahmed R, Amara RR. Akhtar A, et al. Among authors: tharp gk. Nat Immunol. 2025 Nov;26(11):2045-2058. doi: 10.1038/s41590-025-02309-1. Epub 2025 Oct 15. Nat Immunol. 2025. PMID: 41094203 Free PMC article.
Altered Response Pattern following AZD5582 Treatment of SIV-Infected, ART-Suppressed Rhesus Macaque Infants.
Bricker KM, Obregon-Perko V, Williams B, Oliver D, Uddin F, Neja M, Hopkins L, Dashti A, Jean S, Wood JS, Ehnert S, Liang S, Vanderford T, Tharp GK, Bosinger SE, Schauer AP, Mavigner M, Cottrell ML, Margolis D, Dunham RM, Chahroudi A. Bricker KM, et al. Among authors: tharp gk. J Virol. 2022 Apr 13;96(7):e0169921. doi: 10.1128/jvi.01699-21. Epub 2022 Mar 16. J Virol. 2022. PMID: 35293766 Free PMC article.
Adolescent stress sensitizes the adult neuroimmune transcriptome and leads to sex-specific microglial and behavioral phenotypes.
Bekhbat M, Mukhara D, Dozmorov MG, Stansfield JC, Benusa SD, Hyer MM, Rowson SA, Kelly SD, Qin Z, Dupree JL, Tharp GK, Tansey MG, Neigh GN. Bekhbat M, et al. Among authors: tharp gk. Neuropsychopharmacology. 2021 Apr;46(5):949-958. doi: 10.1038/s41386-021-00970-2. Epub 2021 Feb 8. Neuropsychopharmacology. 2021. PMID: 33558677 Free PMC article.
Nef-Mediated CD3-TCR Downmodulation Dampens Acute Inflammation and Promotes SIV Immune Evasion.
Joas S, Sauermann U, Roshani B, Klippert A, Daskalaki M, Mätz-Rensing K, Stolte-Leeb N, Heigele A, Tharp GK, Gupta PM, Nelson S, Bosinger S, Parodi L, Giavedoni L, Silvestri G, Sauter D, Stahl-Hennig C, Kirchhoff F. Joas S, et al. Among authors: tharp gk. Cell Rep. 2020 Feb 18;30(7):2261-2274.e7. doi: 10.1016/j.celrep.2020.01.069. Cell Rep. 2020. PMID: 32075764 Free PMC article.
A new rhesus macaque assembly and annotation for next-generation sequencing analyses.
Zimin AV, Cornish AS, Maudhoo MD, Gibbs RM, Zhang X, Pandey S, Meehan DT, Wipfler K, Bosinger SE, Johnson ZP, Tharp GK, Marçais G, Roberts M, Ferguson B, Fox HS, Treangen T, Salzberg SL, Yorke JA, Norgren RB Jr. Zimin AV, et al. Among authors: tharp gk. Biol Direct. 2014 Oct 14;9(1):20. doi: 10.1186/1745-6150-9-20. Biol Direct. 2014. PMID: 25319552 Free PMC article.
Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention.
Furlan SN, Watkins B, Tkachev V, Flynn R, Cooley S, Ramakrishnan S, Singh K, Giver C, Hamby K, Stempora L, Garrett A, Chen J, Betz KM, Ziegler CG, Tharp GK, Bosinger SE, Promislow DE, Miller JS, Waller EK, Blazar BR, Kean LS. Furlan SN, et al. Among authors: tharp gk. Sci Transl Med. 2015 Nov 25;7(315):315ra191. doi: 10.1126/scitranslmed.aad3231. Sci Transl Med. 2015. PMID: 26606970 Free PMC article.
Decreased T Follicular Regulatory Cell/T Follicular Helper Cell (TFH) in Simian Immunodeficiency Virus-Infected Rhesus Macaques May Contribute to Accumulation of TFH in Chronic Infection.
Chowdhury A, Del Rio Estrada PM, Tharp GK, Trible RP, Amara RR, Chahroudi A, Reyes-Teran G, Bosinger SE, Silvestri G. Chowdhury A, et al. Among authors: tharp gk. J Immunol. 2015 Oct 1;195(7):3237-47. doi: 10.4049/jimmunol.1402701. Epub 2015 Aug 21. J Immunol. 2015. PMID: 26297764 Free PMC article.
76 results