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Endoplasmic Reticulum Stress Contributes to Mitochondrial Exhaustion of CD8⁺ T Cells.

Hurst KE, Lawrence KA, Essman MT, Walton ZJ, Leddy LR, Thaxton JE. Hurst KE, et al. Among authors: thaxton je. Cancer Immunol Res. 2019 Mar;7(3):476-486. doi: 10.1158/2326-6066.CIR-18-0182. Epub 2019 Jan 18. Cancer Immunol Res. 2019. PMID: 30659052 Free PMC article.

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Ex vivo blockade of PI3K gamma or delta signaling enhances the antitumor potency of adoptively transferred CD8⁺ T cells.

Dwyer CJ, Arhontoulis DC, Rangel Rivera GO, Knochelmann HM, Smith AS, Wyatt MM, Rubinstein MP, Atkinson C, Thaxton JE, Neskey DM, Paulos CM. Dwyer CJ, et al. Among authors: thaxton je. Eur J Immunol. 2020 Sep;50(9):1386-1399. doi: 10.1002/eji.201948455. Epub 2020 May 28. Eur J Immunol. 2020. PMID: 32383488 Free PMC article.

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Remodeling Translation Primes CD8⁺ T-cell Antitumor Immunity.

Hurst KE, Lawrence KA, Robino RA, Ball LE, Chung D, Thaxton JE. Hurst KE, et al. Among authors: thaxton je. Cancer Immunol Res. 2020 May;8(5):587-595. doi: 10.1158/2326-6066.CIR-19-0516. Epub 2020 Feb 19. Cancer Immunol Res. 2020. PMID: 32075802 Free article.

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Stress relief for cancer immunotherapy: implications for the ER stress response in tumor immunity.

Andrews AM, Tennant MD, Thaxton JE. Andrews AM, et al. Among authors: thaxton je. Cancer Immunol Immunother. 2021 May;70(5):1165-1175. doi: 10.1007/s00262-020-02740-3. Epub 2020 Oct 26. Cancer Immunol Immunother. 2021. PMID: 33104836 Review.

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An observational study and randomized trial of stress reactivity in cancer disparities.

Halbert CH, Jefferson MS, Danielson C, Froeliger B, Giordano A, Thaxton JE. Halbert CH, et al. Among authors: thaxton je. Health Psychol. 2020 Sep;39(9):745-757. doi: 10.1037/hea0000882. Health Psychol. 2020. PMID: 32833476 Clinical Trial.

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Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94.

Ansa-Addo EA, Thaxton J, Hong F, Wu BX, Zhang Y, Fugle CW, Metelli A, Riesenberg B, Williams K, Gewirth DT, Chiosis G, Liu B, Li Z. Ansa-Addo EA, et al. Among authors: thaxton j. Curr Top Med Chem. 2016;16(25):2765-78. doi: 10.2174/1568026616666160413141613. Curr Top Med Chem. 2016. PMID: 27072698 Free PMC article. Review.

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Endoplasmic Reticulum Protein Disulfide Isomerase Shapes T Cell Efficacy for Adoptive Cellular Therapy of Tumors.

Hurst KE, Lawrence KA, Reyes Angeles L, Ye Z, Zhang J, Townsend DM, Dolloff N, Thaxton JE. Hurst KE, et al. Among authors: thaxton je. Cells. 2019 Nov 26;8(12):1514. doi: 10.3390/cells8121514. Cells. 2019. PMID: 31779147 Free PMC article.

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Interleukin-10: a multi-faceted agent of pregnancy.

Thaxton JE, Sharma S. Thaxton JE, et al. Am J Reprod Immunol. 2010 Jun;63(6):482-91. doi: 10.1111/j.1600-0897.2010.00810.x. Epub 2010 Feb 16. Am J Reprod Immunol. 2010. PMID: 20163400 Free PMC article. Review.

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TLR-mediated preterm birth in response to pathogenic agents.

Thaxton JE, Nevers TA, Sharma S. Thaxton JE, et al. Infect Dis Obstet Gynecol. 2010;2010:378472. doi: 10.1155/2010/378472. Epub 2010 Aug 23. Infect Dis Obstet Gynecol. 2010. PMID: 20827416 Free PMC article. Review.

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To affinity and beyond: harnessing the T cell receptor for cancer immunotherapy.

Thaxton JE, Li Z. Thaxton JE, et al. Hum Vaccin Immunother. 2014;10(11):3313-21. doi: 10.4161/21645515.2014.973314. Hum Vaccin Immunother. 2014. PMID: 25483644 Free PMC article. Review.

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