The virtual cell: an integrated modeling environment for experimental and computational cell biology.
Ann N Y Acad Sci. 2002.
PMID: 12438191
No abstract available.
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The virtual cell: an integrated modeling environment for experimental and computational cell biology.
Ann N Y Acad Sci. 2002 Oct;971:595-6. doi: 10.1111/j.1749-6632.2002.tb04535.x.
Ann N Y Acad Sci. 2002.
PMID: 12438191
No abstract available.
Development of a Virtual Cell Model to Predict Cell Response to Substrate Topography.
ACS Nano. 2017 Sep 26;11(9):9084-9092. doi: 10.1021/acsnano.7b03732. Epub 2017 Jul 30.
ACS Nano. 2017.
PMID: 28742318
Free article.
Here, we developed a unifying computational framework to create a multicomponent cell model, called the "virtual cell model" that has the capability to predict changes in whole cell and cell nucleus characteristics (in terms …
Here, we developed a unifying computational framework to create a multicomponent cell model, called the "virtual …
cellPACK: a virtual mesoscope to model and visualize structural systems biology.
Nat Methods. 2015 Jan;12(1):85-91. doi: 10.1038/nmeth.3204. Epub 2014 Dec 1.
Nat Methods. 2015.
PMID: 25437435
Free PMC article.
cellPACK assembles computational models of the biological mesoscale, an intermediate scale (10-100 nm) between molecular and cellular biology scales. cellPACK's modular architecture unites existing and novel packing algorithms to generate, visualize an …
cellPACK assembles computational models of the biological mesoscale, an intermediate scale (10-100 nm) between molecular and c …
Multiscale mechanobiology of de novo bone generation, remodeling and adaptation of autograft in a common ovine femur model.
J Mech Behav Biomed Mater. 2011 Aug;4(6):829-40. doi: 10.1016/j.jmbbm.2011.03.009. Epub 2011 Mar 16.
J Mech Behav Biomed Mater. 2011.
PMID: 21616464
Free PMC article.
Review.
To address this, here we integrate insights from our previously published studies describing the mechanobiology on both de novo bone generation and graft healing in a common ovine femoral defect model. ...Furthermore, these insights provide a foundation to create …
To address this, here we integrate insights from our previously published studies describing the mechanobiology on both de novo bone …
Predicting Nano-Bio Interactions by Integrating Nanoparticle Libraries and Quantitative Nanostructure Activity Relationship Modeling.
ACS Nano. 2017 Dec 26;11(12):12641-12649. doi: 10.1021/acsnano.7b07093. Epub 2017 Nov 22.
ACS Nano. 2017.
PMID: 29149552
Free PMC article.
The experimental testing results of the designed nanoparticles were consistent with the model predictions. These findings demonstrate that rational design approaches combining high-quality nanoparticle libraries, big experimental data sets, and intelligent …
The experimental testing results of the designed nanoparticles were consistent with the model predictions. These findings demo …
Evolution of taxis responses in virtual bacteria: non-adaptive dynamics.
PLoS Comput Biol. 2008 May 23;4(5):e1000084. doi: 10.1371/journal.pcbi.1000084.
PLoS Comput Biol. 2008.
PMID: 18483577
Free PMC article.
This approach starts with a population of virtual bacteria that move in a virtual environment based on the dynamics of the simple biochemical pathways they harbour. ...We find that a certain dynamics evolves consistently under different model assumptio …
This approach starts with a population of virtual bacteria that move in a virtual environment based on the dynamics of …
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