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The ABC (age, biomarkers, clinical history) stroke risk score: a biomarker-based risk score for predicting stroke in atrial fibrillation.
Hijazi Z, Lindbäck J, Alexander JH, Hanna M, Held C, Hylek EM, Lopes RD, Oldgren J, Siegbahn A, Stewart RA, White HD, Granger CB, Wallentin L; ARISTOTLE and STABILITY Investigators. Hijazi Z, et al. Eur Heart J. 2016 May 21;37(20):1582-90. doi: 10.1093/eurheartj/ehw054. Epub 2016 Feb 25. Eur Heart J. 2016. PMID: 26920728 Free PMC article.
AIMS: Atrial fibrillation (AF) is associated with an increased risk of stroke, which is currently estimated by clinical characteristics. ...The most important predictors were prior stroke/transient ischaemic attack, NT-proBNP, cTn-hs, and …
AIMS: Atrial fibrillation (AF) is associated with an increased risk of stroke, which is currently estimated by …
Biomarkers for Risk Assessment in Atrial Fibrillation.
Berg DD, Ruff CT, Morrow DA. Berg DD, et al. Clin Chem. 2021 Jan 8;67(1):87-95. doi: 10.1093/clinchem/hvaa298. Clin Chem. 2021. PMID: 33313695 Review.
BACKGROUND: Atrial fibrillation (AF) is associated with an increased risk of thromboembolism, which can be significantly reduced with anticoagulant treatment. ...The biomarker-based age, biomarker, clinical history ( …
BACKGROUND: Atrial fibrillation (AF) is associated with an increased risk of thromboembolism, which can be significantl …
The novel biomarker-based ABC (age, biomarkers, clinical history)-bleeding risk score for patients with atrial fibrillation: a derivation and validation study.
Hijazi Z, Oldgren J, Lindbäck J, Alexander JH, Connolly SJ, Eikelboom JW, Ezekowitz MD, Held C, Hylek EM, Lopes RD, Siegbahn A, Yusuf S, Granger CB, Wallentin L; ARISTOTLE and RE-LY Investigators. Hijazi Z, et al. Lancet. 2016 Jun 4;387(10035):2302-2311. doi: 10.1016/S0140-6736(16)00741-8. Epub 2016 Apr 4. Lancet. 2016. PMID: 27056738 Clinical Trial.
We aimed to develop and validate a new biomarker-based risk score to improve the prognostication of major bleeding in patients with atrial fibrillation. METHODS: We developed and internally validated a new biomarker-based …
We aimed to develop and validate a new biomarker-based risk score to improve the prognostication of major bleedi …
Biomarker-Based Model for Prediction of Ischemic Stroke in Patients With Atrial Fibrillation.
Wallentin L, Lindbäck J, Hijazi Z, Oldgren J, Carnicelli AP, Alexander JH, Berg DD, Eikelboom JW, Goto S, Lopes RD, Ruff CT, Siegbahn A, Giugliano RP, Granger CB, Morrow DA. Wallentin L, et al. J Am Coll Cardiol. 2025 Mar 25;85(11):1173-1185. doi: 10.1016/j.jacc.2024.11.052. J Am Coll Cardiol. 2025. PMID: 40107814 Free article.
OBJECTIVES: The authors evaluated the biomarker-based Age, Biomarkers, Clinical history (ABC)-AF-stroke risk score and developed a modified ABC-AF-istroke risk score for prediction o …
OBJECTIVES: The authors evaluated the biomarker-based Age, Biomarkers, Clinical history (ABC …
The ABC-Stroke Score Refines Stroke Risk Stratification in Patients With Atrial Fibrillation at the Emergency Department.
Niederdöckl J, Oppenauer J, Schnaubelt S, Cacioppo F, Buchtele N, Warenits AM, Laggner R, Schütz N, Bögl MS, Ruzicka G, Gupta S, Lutnik M, Sheikh Rezaei S, Wolzt M, Herkner H, Domanovits H, Laggner AN, Schwameis M, Hijazi Z. Niederdöckl J, et al. Front Med (Lausanne). 2022 Jun 27;9:830580. doi: 10.3389/fmed.2022.830580. eCollection 2022. Front Med (Lausanne). 2022. PMID: 35833107 Free PMC article.
METHODS AND RESULTS: The performance of the biomarker-based ABC-stroke score and the clinical variable-based CHA(2)DS(2)-VASc score for stroke risk assessment were prospectively evaluated in a consecutive series of 2, …
METHODS AND RESULTS: The performance of the biomarker-based ABC-stroke score and the clinical vari …
Biomarker-Based Risk Prediction With the ABC-AF Scores in Patients With Atrial Fibrillation Not Receiving Oral Anticoagulation.
Benz AP, Hijazi Z, Lindbäck J, Connolly SJ, Eikelboom JW, Oldgren J, Siegbahn A, Wallentin L. Benz AP, et al. Circulation. 2021 May 11;143(19):1863-1873. doi: 10.1161/CIRCULATIONAHA.120.053100. Epub 2021 Apr 14. Circulation. 2021. PMID: 33849281
BACKGROUND: The novel ABC (Age, Biomarkers, Clinical History) scores outperform traditional risk scores for stroke, major bleeding, and death in patients with atrial fibrillation (AF) receiving oral anticoagulation. . …
BACKGROUND: The novel ABC (Age, Biomarkers, Clinical History) scores outperform traditional risk s …
Repeated Measurements of Cardiac Biomarkers in Atrial Fibrillation and Validation of the ABC Stroke Score Over Time.
Hijazi Z, Lindahl B, Oldgren J, Andersson U, Lindbäck J, Granger CB, Alexander JH, Gersh BJ, Hanna M, Harjola VP, Hylek EM, Lopes RD, Siegbahn A, Wallentin L. Hijazi Z, et al. J Am Heart Assoc. 2017 Jun 23;6(6):e004851. doi: 10.1161/JAHA.116.004851. J Am Heart Assoc. 2017. PMID: 28645934 Free PMC article. Clinical Trial.
BACKGROUND: Cardiac biomarkers are independent risk markers in atrial fibrillation, and the novel biomarker-based ABC stroke score (age, biomarkers, and clinical history of prior stroke …
BACKGROUND: Cardiac biomarkers are independent risk markers in atrial fibrillation, and the novel biomarker …
Evaluation of the updated ABC-AF-bleeding score 2.0 in patients with atrial fibrillation treated with a direct oral anticoagulant or warfarin.
Hijazi Z, Lindbäck J, Oldgren J, Alexander JH, Benz AP, Berg DD, Carnicelli AP, Eikelboom JW, Giugliano RP, Goto S, Granger CB, Lopes RD, Ruff CT, Siegbahn A, Morrow DA, Wallentin L. Hijazi Z, et al. J Thromb Haemost. 2026 Feb;24(2):399-407. doi: 10.1016/j.jtha.2025.09.032. J Thromb Haemost. 2026. PMID: 41644239 Free article.
BACKGROUND: Oral anticoagulation (OAC) reduces stroke in patients with atrial fibrillation (AF), but increases bleeding. OBJECTIVES: This study aimed to evaluate an updated version of the Age, Biomarkers, and Clinical history of bl …
BACKGROUND: Oral anticoagulation (OAC) reduces stroke in patients with atrial fibrillation (AF), but increases bleeding …