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Familial Risk and Heritability of Cancer Among Twins in Nordic Countries.
Mucci LA, Hjelmborg JB, Harris JR, Czene K, Havelick DJ, Scheike T, Graff RE, Holst K, Möller S, Unger RH, McIntosh C, Nuttall E, Brandt I, Penney KL, Hartman M, Kraft P, Parmigiani G, Christensen K, Koskenvuo M, Holm NV, Heikkilä K, Pukkala E, Skytthe A, Adami HO, Kaprio J; Nordic Twin Study of Cancer (NorTwinCan) Collaboration. Mucci LA, et al. JAMA. 2016 Jan 5;315(1):68-76. doi: 10.1001/jama.2015.17703. JAMA. 2016. PMID: 26746459 Free PMC article.
Time-to-event analyses were used to estimate familial risk (risk of cancer in an individual given a twin's development of cancer) and heritability (proportion of variance in cancer risk due to interindividual genetic differences) with fol …
Time-to-event analyses were used to estimate familial risk (risk of cancer in an individual given a twin's development …
The heritability of prostate cancer in the Nordic Twin Study of Cancer.
Hjelmborg JB, Scheike T, Holst K, Skytthe A, Penney KL, Graff RE, Pukkala E, Christensen K, Adami HO, Holm NV, Nuttall E, Hansen S, Hartman M, Czene K, Harris JR, Kaprio J, Mucci LA. Hjelmborg JB, et al. Cancer Epidemiol Biomarkers Prev. 2014 Nov;23(11):2303-10. doi: 10.1158/1055-9965.EPI-13-0568. Epub 2014 May 8. Cancer Epidemiol Biomarkers Prev. 2014. PMID: 24812039 Free PMC article.
BACKGROUND: Prostate cancer is thought to be the most heritable cancer, although little is known about how this genetic contribution varies across age. METHODS: To address this question, we undertook the world's largest prospective study
BACKGROUND: Prostate cancer is thought to be the most heritable cancer, although little is known about how this …
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