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The prevalence and clinical correlates of apathy and irritability in Alzheimer's disease.
Starkstein SE, Migliorelli R, Manes F, Tesón A, Petracca G, Chemerinski E, Sabe L, Leiguarda R. Starkstein SE, et al. Eur J Neurol. 1995 Dec;2(6):540-6. doi: 10.1111/j.1468-1331.1995.tb00171.x. Eur J Neurol. 1995. PMID: 24283780
We examined the prevalence and correlates of apathy and irritability in a consecutive series of 101 patients with probable Alzheimer's disease (AD). Based on clinical criteria, 46 (46%) patients had apathy, and 13 (13 …
We examined the prevalence and correlates of apathy and irritability in a consecutive series of 101 patients wit …
Clinical Correlates of Depression and Suicidality in Huntington Disease: An Analysis of the Enroll-HD Observational Study.
Rocha NP, Tuazon MR, Patino J, Furr Stimming E, Teixeira AL. Rocha NP, et al. Cogn Behav Neurol. 2022 Jun 1;35(2):85-94. doi: 10.1097/WNN.0000000000000301. Cogn Behav Neurol. 2022. PMID: 35486527
BACKGROUND: Depression and suicidality are commonly experienced by Huntington disease (HD) gene carriers. Research on these behavioral symptoms is imperative, not only to increase our understanding of the symptoms and how they relate to HD, but also to contribute to improv …
BACKGROUND: Depression and suicidality are commonly experienced by Huntington disease (HD) gene carriers. Research on these behaviora …
Neuropsychiatric symptom clusters of Alzheimer's disease in Hong Kong Chinese: prevalence and confirmatory factor analysis of the Neuropsychiatric Inventory.
Cheng ST, Kwok T, Lam LC. Cheng ST, et al. Int Psychogeriatr. 2012 Sep;24(9):1465-73. doi: 10.1017/S1041610212000609. Epub 2012 Apr 25. Int Psychogeriatr. 2012. PMID: 22717370
BACKGROUND: The aim of this study was to investigate the clustering of symptoms on the Neuropsychiatric Inventory (NPI) and the relative prevalence of symptom clusters in mild and moderate Alzheimer's disease (AD). ...The most prevalent symptom …
BACKGROUND: The aim of this study was to investigate the clustering of symptoms on the Neuropsychiatric Inventory (NPI) and the relative …
Relationship between neuropsychiatric symptoms and cognitive functions in patients with cognitive impairment.
Lü W, Duan J, Zhang W, Yang W, Yu W. Lü W, et al. Psychogeriatrics. 2021 Sep;21(5):773-782. doi: 10.1111/psyg.12738. Epub 2021 Jul 3. Psychogeriatrics. 2021. PMID: 34216181
BACKGROUND: Cognitive decline and neuropsychiatric symptoms (NPS) are main clinical manifestations in Alzheimer disease (AD). It is unclear whether the link between specific NPS and cognitive domains exists in AD or mild cognitive impairment (MCI). ...The ass …
BACKGROUND: Cognitive decline and neuropsychiatric symptoms (NPS) are main clinical manifestations in Alzheimer disease
Development of a Thai tool for assessing behavioral and psychological symptoms of dementia: A confirmatory factor analysis.
Phannarus H, Muangpaisan W, Siritipakorn P, Pianchob S, Supapueng O. Phannarus H, et al. Brain Behav. 2020 Nov;10(11):e01816. doi: 10.1002/brb3.1816. Epub 2020 Aug 28. Brain Behav. 2020. PMID: 32857486 Free PMC article.
RESULTS: A total of 168 people with dementia (mean age, 80.7 6.7 years) and their primary caregivers were recruited. A total of 105 (62.5%) subjects were diagnosed with Alzheimer's disease (AD), and 31 (18.5%) with AD with small-vessel disease. ...CONC …
RESULTS: A total of 168 people with dementia (mean age, 80.7 6.7 years) and their primary caregivers were recruited. A total of 105 (62.5%) …
Clinical Trajectories of Neuropsychiatric Symptoms in Mild-Moderate to Advanced Dementia.
Castillo-García IM, López-Álvarez J, Osorio R, Olazarán J, Ramos García MI, Agüera-Ortiz L. Castillo-García IM, et al. J Alzheimers Dis. 2022;86(2):861-875. doi: 10.3233/JAD-215133. J Alzheimers Dis. 2022. PMID: 35147532
RESULTS: Overall prevalence of NPS was 94.6%, being apathy the most prevalent (66.7%) and the one whose severity increased the most with progression of dementia. ...CONCLUSION: NPS in dementia follow a heterogeneous course. Apathy is the most preval
RESULTS: Overall prevalence of NPS was 94.6%, being apathy the most prevalent (66.7%) and the one whose severity increa …
Clustering of behavioural and psychological symptoms in dementia (BPSD): a European Alzheimer's disease consortium (EADC) study.
Petrovic M, Hurt C, Collins D, Burns A, Camus V, Liperoti R, Marriott A, Nobili F, Robert P, Tsolaki M, Vellas B, Verhey F, Byrne EJ. Petrovic M, et al. Acta Clin Belg. 2007 Nov-Dec;62(6):426-32. doi: 10.1179/acb.2007.062. Acta Clin Belg. 2007. PMID: 18351187
METHODS: We recruited 194 patients with dementia from the memory clinic practice of six European Alzheimer's Disease Consortium centres. ...Four NPI-based factors were identified (58% of the common variance): psychosis factor (irritability, agit …
METHODS: We recruited 194 patients with dementia from the memory clinic practice of six European Alzheimer's Disease
Caregiver's distress related to the patient's neuropsychiatric symptoms as a function of the care-setting.
Lorenzo-López L, de Labra C, Maseda A, Lorenzo T, Agrafojo H, Rodríguez-Villamil JL, González-Abraldes I, Millán-Calenti JC. Lorenzo-López L, et al. Geriatr Nurs. 2017 Mar-Apr;38(2):110-118. doi: 10.1016/j.gerinurse.2016.08.004. Epub 2016 Sep 9. Geriatr Nurs. 2017. PMID: 27623026
Prevalence of neuropsychiatric symptoms (NPS) and correlation between its intensity and caregiver distress were evaluated as a function of the care-setting in a cross-sectional study including 72 patient-caregiver dyads. ...While changes in appetite and eatin
Prevalence of neuropsychiatric symptoms (NPS) and correlation between its intensity and caregiver distress were evaluated as a
The neuropsychiatric profile of posterior cortical atrophy.
Isella V, Villa G, Mapelli C, Ferri F, Appollonio IM, Ferrarese C. Isella V, et al. J Geriatr Psychiatry Neurol. 2015 Jun;28(2):136-44. doi: 10.1177/0891988714554713. Epub 2014 Oct 20. J Geriatr Psychiatry Neurol. 2015. PMID: 25330926
We analyzed scores obtained at the Neuropsychiatric Inventory (NPI) by 20 patients with posterior cortical atrophy (PCA) and contrasted it with 20 patients having Alzheimer disease (AD). Patients with hallucinations and delusions were not included due to the high pr …
We analyzed scores obtained at the Neuropsychiatric Inventory (NPI) by 20 patients with posterior cortical atrophy (PCA) and contrasted it w …
Neuropsychiatric symptoms and severity of dementia.
Caldas GHO, Pires SL, Gorzoni ML. Caldas GHO, et al. Dement Neuropsychol. 2013 Apr-Jun;7(2):171-175. doi: 10.1590/S1980-57642013DN70200006. Dement Neuropsychol. 2013. PMID: 29213836 Free PMC article.
RESULTS: The 124 subjects (mean age of 80.47.0 years), 88 women (70.9%) had average duration of dementia of 7.13.2 years, most common dementias of Alzheimer's disease (35.5%) and mixed (31.5%) and most prevalent NPS of apathy (75%) and irrita
RESULTS: The 124 subjects (mean age of 80.47.0 years), 88 women (70.9%) had average duration of dementia of 7.13.2 years, most common dement …
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