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The vanilloid receptor as a putative target of diverse chemicals in multiple chemical sensitivity.
Pall ML, Anderson JH. Pall ML, et al. Arch Environ Health. 2004 Jul;59(7):363-75. doi: 10.3200/AEOH.59.7.363-375. Arch Environ Health. 2004. PMID: 16241041 Review.
Vanilloid receptor activity is markedly altered by multiple mechanisms, possibly providing an explanation for the increased activity in MCS and symptom masking by previous chemical exposure. ...Twelve types of evidence implicate the vanilloid receptor
Vanilloid receptor activity is markedly altered by multiple mechanisms, possibly providing an explanation for the increased ac
Pharmacological effects of cannabidiol by transient receptor potential channels.
Etemad L, Karimi G, Alavi MS, Roohbakhsh A. Etemad L, et al. Life Sci. 2022 Jul 1;300:120582. doi: 10.1016/j.lfs.2022.120582. Epub 2022 Apr 26. Life Sci. 2022. PMID: 35483477 Review.
It has little affinity for classical cannabinoid receptors (CB1 and CB2). Considering this and its diverse pharmacological effects, it is logical to set up studies for finding its putative potential targets other than CB1 and CB2. A class of ion channels
It has little affinity for classical cannabinoid receptors (CB1 and CB2). Considering this and its diverse pharmacological effects, i …
Pharmacological diversity amongst approved and emerging antiseizure medications for the treatment of developmental and epileptic encephalopathies.
Sills GJ. Sills GJ. Ther Adv Neurol Disord. 2023 Aug 30;16:17562864231191000. doi: 10.1177/17562864231191000. eCollection 2023. Ther Adv Neurol Disord. 2023. PMID: 37655228 Free PMC article. Review.
Rufinamide, fenfluramine, stiripentol, cannabidiol and ganaxolone are antiseizure medications (ASMs) with diverse mechanisms of action that have been approved for treating specific DEEs. ...The mechanism(s) of action of cannabidiol remains largely unclear although multiple …
Rufinamide, fenfluramine, stiripentol, cannabidiol and ganaxolone are antiseizure medications (ASMs) with diverse mechanisms of actio …
Antinociception mechanisms of action of cannabinoid-based medicine: an overview for anesthesiologists and pain physicians.
Narouze S. Narouze S. Reg Anesth Pain Med. 2021 Mar;46(3):240-250. doi: 10.1136/rapm-2020-102114. Epub 2020 Nov 25. Reg Anesth Pain Med. 2021. PMID: 33239391 Review.
Cannabinoid-based medications possess unique multimodal analgesic mechanisms of action, modulating diverse pain targets. Cannabinoids are classified based on their origin into three categories: endocannabinoids (present endogenously in human tissues), phytocannabino …
Cannabinoid-based medications possess unique multimodal analgesic mechanisms of action, modulating diverse pain targets. Canna …
Physiology, phylogeny, and functions of the TRP superfamily of cation channels.
Montell C. Montell C. Sci STKE. 2001 Jul 10;2001(90):re1. doi: 10.1126/stke.2001.90.re1. Sci STKE. 2001. PMID: 11752662 Review.
The transient receptor potential (TRP) protein superfamily consists of a diverse group of Ca(2+) permeable nonselective cation channels that bear structural similarities to Drosophila TRP. ...Thus, TRP channels may prove to be important new t
The transient receptor potential (TRP) protein superfamily consists of a diverse group of Ca(2+) permeable nonselective cat