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The enhancement of bone regeneration by gene activated matrix encoding for platelet derived growth factor.
Elangovan S, D'Mello SR, Hong L, Ross RD, Allamargot C, Dawson DV, Stanford CM, Johnson GK, Sumner DR, Salem AK. Elangovan S, et al. Biomaterials. 2014 Jan;35(2):737-47. doi: 10.1016/j.biomaterials.2013.10.021. Epub 2013 Oct 22. Biomaterials. 2014. PMID: 24161167 Free PMC article.
The objective of this study was to develop and test a non-viral gene delivery system for bone regeneration utilizing a collagen scaffold to deliver polyethylenimine (PEI)-plasmid DNA (pDNA) [encoding platelet derived growth fact
The objective of this study was to develop and test a non-viral gene delivery system for bone regeneration utilizing a …
Controlled Co-delivery of pPDGF-B and pBMP-2 from intraoperatively bioprinted bone constructs improves the repair of calvarial defects in rats.
Moncal KK, Tigli Aydın RS, Godzik KP, Acri TM, Heo DN, Rizk E, Wee H, Lewis GS, Salem AK, Ozbolat IT. Moncal KK, et al. Biomaterials. 2021 Dec 28;281:121333. doi: 10.1016/j.biomaterials.2021.121333. Online ahead of print. Biomaterials. 2021. PMID: 34995904
We used a controlled co-delivery release of growth factors from a gene-activated matrix (an osteogenic bioink loaded with plasmid-DNAs (pDNA)) to promote bone repair. The controlled co-delivery approach was achieved from the combination of pl
We used a controlled co-delivery release of growth factors from a gene-activated matrix (an osteogenic bioink lo …